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Calcium: A program in basic for calculating the composition of solutions with specified free concentrations of calcium, magnesium and other divalent cations
dc.contributor.authorChang, Deanen_US
dc.contributor.authorHsieh, Paul S.en_US
dc.contributor.authorDawson, David C.en_US
dc.date.accessioned2006-04-07T20:31:37Z
dc.date.available2006-04-07T20:31:37Z
dc.date.issued1988en_US
dc.identifier.citationChang, Dean, Hsieh, Paul S., Dawson, David C. (1988)."Calcium: A program in basic for calculating the composition of solutions with specified free concentrations of calcium, magnesium and other divalent cations." Computers in Biology and Medicine 18(5): 351-366. <http://hdl.handle.net/2027.42/27545>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T5N-4BY4P8J-C5/2/0f646e3aaef0e9c8c5a2675c0a26345aen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/27545
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3143515&dopt=citationen_US
dc.description.abstractA BASIC program is presented which facilitates the formulation of biologically relevant chemical solutions containing specified free concentrations of as many as three divalent metal cations (Ca2+, Mg2+ and the choice of a third divalent cation) at any pH in the presence of as many as three ligands (EGTA, ATP and GTP). The program uses the law of mass action and the absolute stability (association) constants found in the literature to calculate the total concentration of divalent metal cation needed to achieve a desired free concentration. The user enters the pH, the concentrations of the ligands used and the desired free concentrations of the divalent cations. This program was developed for use in a wide range of biological applications, particularly the rapid design of solutions which mimic certain aspects of intracellular fluid.en_US
dc.format.extent887966 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleCalcium: A program in basic for calculating the composition of solutions with specified free concentrations of calcium, magnesium and other divalent cationsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelComputer Scienceen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Physiology and Cellular Box 0622, University of Michigan Medical School, Ann Arbor, MI 48109-0622, U.S.A.; Molecular Biology Program 6811 Medical Science II, Box 0622, University of Michigan Medical School, Ann Arbor, MI 48109-0622, U.S.A.en_US
dc.contributor.affiliationumDepartment of Physiology and Cellular Box 0622, University of Michigan Medical School, Ann Arbor, MI 48109-0622, U.S.A.; Molecular Biology Program 6811 Medical Science II, Box 0622, University of Michigan Medical School, Ann Arbor, MI 48109-0622, U.S.A.en_US
dc.contributor.affiliationumDepartment of Physiology and Cellular Box 0622, University of Michigan Medical School, Ann Arbor, MI 48109-0622, U.S.A.; Molecular Biology Program 6811 Medical Science II, Box 0622, University of Michigan Medical School, Ann Arbor, MI 48109-0622, U.S.A.en_US
dc.identifier.pmid3143515en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/27545/1/0000589.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0010-4825(88)90022-4en_US
dc.identifier.sourceComputers in Biology and Medicineen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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