Show simple item record

1,4-Additions of the highly functionalized copper reagents RCu(CN)ZnI [middle dot] 2 BFP3 to trisubstituted enones. A new BF3 promoted cyclization reaction

dc.contributor.authorYeh, Ming Chang P.en_US
dc.contributor.authorKnochel, Paulen_US
dc.contributor.authorButler, William M.en_US
dc.contributor.authorBerk, Scott C.en_US
dc.date.accessioned2006-04-07T20:34:29Z
dc.date.available2006-04-07T20:34:29Z
dc.date.issued1988en_US
dc.identifier.citationYeh, Ming Chang P., Knochel,, Paul, Butler, William M., Berk, Scott C. (1988)."1,4-Additions of the highly functionalized copper reagents RCu(CN)ZnI [middle dot] 2 BFP3 to trisubstituted enones. A new BF3 promoted cyclization reaction." Tetrahedron Letters 29(51): 6693-6696. <http://hdl.handle.net/2027.42/27620>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6THS-42HPFMY-CB/2/ed64db0874e511d4f3e34e54f8e65941en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/27620
dc.description.abstractThe new copper reagents RCu(CN)Zn I [middle dot] 2 BF3 1 containing various functional groups like esters, cyanides, chlorides or enoates react with [beta], [beta]'- disubstituted enones to afford the Michael adducts 4-7 in high yields (81-98%). Cyano-substituted 1,4-adducts undergo a new cyclization reaction leading to the very stable bicyclic difluoroboron enolates 11a-11c which could be converted into the bicyclic diketones 12 under mild basic conditions. The X-ray structure of 11b is reported.en_US
dc.format.extent213273 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.title1,4-Additions of the highly functionalized copper reagents RCu(CN)ZnI [middle dot] 2 BFP3 to trisubstituted enones. A new BF3 promoted cyclization reactionen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMaterials Science and Engineeringen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Chemistry, The University of Michigan, Ann Arbor, Michigan 48109 USAen_US
dc.contributor.affiliationumDepartment of Chemistry, The University of Michigan, Ann Arbor, Michigan 48109 USAen_US
dc.contributor.affiliationumDepartment of Chemistry, The University of Michigan, Ann Arbor, Michigan 48109 USAen_US
dc.contributor.affiliationumDepartment of Chemistry, The University of Michigan, Ann Arbor, Michigan 48109 USAen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/27620/1/0000664.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/S0040-4039(00)82430-2en_US
dc.identifier.sourceTetrahedron Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Show simple item record