Nitric oxide: biosynthesis and biological significance
dc.contributor.author | Marletta, Michael A. | en_US |
dc.date.accessioned | 2006-04-07T20:38:22Z | |
dc.date.available | 2006-04-07T20:38:22Z | |
dc.date.issued | 1989-12 | en_US |
dc.identifier.citation | Marletta, Michael A. (1989/12)."Nitric oxide: biosynthesis and biological significance." Trends in Biochemical Sciences 14(12): 488-492. <http://hdl.handle.net/2027.42/27667> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TCV-4864CB0-75/2/4774e634c124164c7f663c3c7672c705 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/27667 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2696179&dopt=citation | en_US |
dc.description.abstract | The recent discovery that mammalian cells can synthesize nitric oxide coincided with the identification of this simple gas as a factor involved in cellular communication. Nitric oxide has now been shown to be derived from -arginine in macrophages, endothelial cells and possibly other cell types. Its physiological role in macrophages may be as a cytotoxic agent. However, nitric oxide produced by endothelial cells is thought to trigger vascular smooth muscle relaxation through activation of the enzyme guanylate cyclase. | en_US |
dc.format.extent | 657701 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Nitric oxide: biosynthesis and biological significance | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | College of Pharmacy and Department of Biological Chemistry School of Medicine, The University of Michigan, 428 Church Street, Ann Arbor, MI 48109-1065, USA | en_US |
dc.identifier.pmid | 2696179 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/27667/1/0000049.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0968-0004(89)90181-3 | en_US |
dc.identifier.source | Trends in Biochemical Sciences | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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