Cholecystokinin receptor antagonism of stimulated pancreatic and gastric secretion
dc.contributor.author | Mulholland, Michael W. | en_US |
dc.contributor.author | Debas, Haile T. | en_US |
dc.date.accessioned | 2006-04-07T20:39:54Z | |
dc.date.available | 2006-04-07T20:39:54Z | |
dc.date.issued | 1989-11 | en_US |
dc.identifier.citation | Mulholland, Michael W., Debas, Haile T. (1989/11)."Cholecystokinin receptor antagonism of stimulated pancreatic and gastric secretion." Journal of Surgical Research 47(5): 460-464. <http://hdl.handle.net/2027.42/27708> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WM6-4BNF2MK-233/2/c7cb789bf36918148896dbe0a27b24f7 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/27708 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2478762&dopt=citation | en_US |
dc.description.abstract | The effects of cholecystokinin receptor antagonist, dipentyl-3,4-dichloroproglumide (DDP), on stimulated pancreatic and gastric secretion were studied in the rat. DDP dose-dependently inhibited cholecystokinin-stimulated amylase release from dispersed acinar cells. In vivo, DDP inhibited cholecystokinin octapeptide-stimulated amylase and protein secretion. DDP also inhibited pentagastrin-stimulated gastric acid secretion in vivo. Meal-stimulated acid output was decreased by 34% (DDP 400 [mu]g/kg/hr) but responsiveness to histamine or parachlorophenyl-[gamma]-aminobutyric acid was unchanged. | en_US |
dc.format.extent | 592080 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Cholecystokinin receptor antagonism of stimulated pancreatic and gastric secretion | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Surgery and Anesthesiology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Surgery, University of Michigan, Ann Arbor, Michigan 49109, USA | en_US |
dc.contributor.affiliationother | Department of Surgery, University of California, San Francisco, California 94143, USA | en_US |
dc.identifier.pmid | 2478762 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/27708/1/0000094.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0022-4804(89)90102-9 | en_US |
dc.identifier.source | Journal of Surgical Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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