Drug-reinforced responding: rapid determination of dose-response functions
dc.contributor.author | Winger, Gail D. | en_US |
dc.contributor.author | Palmer, R. Kyle | en_US |
dc.contributor.author | Woods, James H. | en_US |
dc.date.accessioned | 2006-04-07T20:40:34Z | |
dc.date.available | 2006-04-07T20:40:34Z | |
dc.date.issued | 1989-10 | en_US |
dc.identifier.citation | Winger, G., Palmer, R. K., Woods, J. H. (1989/10)."Drug-reinforced responding: rapid determination of dose-response functions." Drug and Alcohol Dependence 24(2): 135-142. <http://hdl.handle.net/2027.42/27725> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T63-4BWFB65-26/2/6d4a78d518c79f6136881018e33b5780 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/27725 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2676442&dopt=citation | en_US |
dc.description.abstract | Rhesus monkeys were conditioned to press on levers and receive intravenous infusions of cocaine or ketamine. Experimental conditions provided several different doses of drug during each of two daily 130 min sessions; as a result, a doseresponse curve relating rate of responding to dose/injection for self-administered drug was obtained within each session. Relative rate-maintaining effects of nomifensine and cocaine in monkeys on baseline conditions of cocaine self-administration, and rate-maintaining effects of ketamine, phencyclidine and MK-801 in monkeys on baseline conditions of ketamine self-administration, compared favorably with relative rate-maintaining effects of these substances obtained in more traditional paradigms. | en_US |
dc.format.extent | 696891 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Drug-reinforced responding: rapid determination of dose-response functions | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Social Work | en_US |
dc.subject.hlbsecondlevel | Psychology | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Social Sciences | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Psychology, University of Michigan, Ann Arbor, MI 48109, U.S.A.; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.identifier.pmid | 2676442 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/27725/1/0000117.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0376-8716(89)90076-8 | en_US |
dc.identifier.source | Drug and Alcohol Dependence | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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