Neurobehavioral effects of prenatal alcohol: Part III. PLS analyses of neuropsychologic tests
dc.contributor.author | Streissguth, Ann P. | en_US |
dc.contributor.author | Bookstein, Fred L. | en_US |
dc.contributor.author | Sampson, Paul D. | en_US |
dc.contributor.author | Barr, Helen M. | en_US |
dc.date.accessioned | 2006-04-07T20:43:01Z | |
dc.date.available | 2006-04-07T20:43:01Z | |
dc.date.issued | 1989 | en_US |
dc.identifier.citation | Streissguth, Ann P., Bookstein, Fred L., Sampson, Paul D., Barr, Helen M. (1989)."Neurobehavioral effects of prenatal alcohol: Part III. PLS analyses of neuropsychologic tests." Neurotoxicology and Teratology 11(5): 493-507. <http://hdl.handle.net/2027.42/27791> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T9X-47RWNT8-85/2/bb413f7138b7ad9a772c387b0a9c68fd | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/27791 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2593988&dopt=citation | en_US |
dc.description.abstract | This paper is the third in a three-part series describing an investigation of the effects of prenatal alcohol exposure on the neurobehavioral functioning of 384 children about years old. Here we describe the use of Partial Least Squares for data reduction and analysis of 158 neurobehavioral measures as they relate to 13 aspects of prenatal alcohol exposure. A general alcohol latent variable, emphasizing both binge and regular drinking patterns in the period prior to pregnancy recognition as well as during pregnancy, predicts a pattern of neurobehavioral deficit that includes attentional and memory deficits across both verbal and visual modalities; a variety of "process" variables reflecting poor integration and quality of responses; behavior patterns involving distractibility and poor organization; and an inflexible approach to problem-solving. The prominence of poorer spatial organization and arithmetic as primary outcomes of alcohol teratogenesis suggests a possible "nonverbal learning disability" pattern of deficit associated with prenatal alcohol exposure at the level of social drinking. | en_US |
dc.format.extent | 1327044 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Neurobehavioral effects of prenatal alcohol: Part III. PLS analyses of neuropsychologic tests | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationother | Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA; Alcoholism and Drug Abuse Institute, University of Washington, Seattle, WA 98195, USA; Child Development/Mental Retardation Center, University of Washington, Seattle, WA 98195, USA. | en_US |
dc.contributor.affiliationother | Department of Statistics, University of Washington, Seattle, WA 98195, USA | en_US |
dc.contributor.affiliationother | Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA | en_US |
dc.identifier.pmid | 2593988 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/27791/1/0000189.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0892-0362(89)90026-3 | en_US |
dc.identifier.source | Neurotoxicology and Teratology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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