Quantitative autoradiographic localization of NMDA, quisqualate and PCP receptors in the frog tectum
dc.contributor.author | McDonald, John W. | en_US |
dc.contributor.author | Cline, Hollis T. | en_US |
dc.contributor.author | Constantine-Paton, Martha | en_US |
dc.contributor.author | Maragos, William F. | en_US |
dc.contributor.author | Johnston, Michael V. | en_US |
dc.contributor.author | Young, Anne B. | en_US |
dc.date.accessioned | 2006-04-07T20:52:14Z | |
dc.date.available | 2006-04-07T20:52:14Z | |
dc.date.issued | 1989-03-13 | en_US |
dc.identifier.citation | McDonald, John W., Cline, Hollis T., Constantine-Paton, Martha, Maragos, William F., Johnston, Michael V., Young, Anne B. (1989/03/13)."Quantitative autoradiographic localization of NMDA, quisqualate and PCP receptors in the frog tectum." Brain Research 482(1): 155-158. <http://hdl.handle.net/2027.42/28018> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6SYR-483SVTH-2WY/2/af80b26fce43c2b6d3fc2fd9588a21c4 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/28018 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2539881&dopt=citation | en_US |
dc.description.abstract | An organizing role for the (NMDA) receptor/channel has been suggested in the development of the retinotectal projection in Rana pipiens. The regional distributions of NMDA, phencyclidine (PCP) and quisqualic acid (QA) receptors were quantified using in vitro autoradiography in the tectum of normal and surgically produced 3-eyed juvenile frogs. NMDA and QA receptor binding was highest in the pretectum. Of the tectal layers, the superficial retinotectal synaptic zone, layer 9, had the highest amount of NMDA and QA receptor binding. Moderate binding was observed in layer 5, with little binding in the cellular layer 6. No specific [3H]N-(1-[2-thienyl]cyclohexyl piperidine ([3H]TCP) binding was observed in any of the tectal regions. | en_US |
dc.format.extent | 348058 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Quantitative autoradiographic localization of NMDA, quisqualate and PCP receptors in the frog tectum | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Neuroscience and Medical Scientists Training Program, University of Michigan, Ann Arbor, MI, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Neurology, University of Michigan, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Department of Neurology, University of Michigan, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Department of Neurology, University of Michigan, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationother | Department of Biology, Yale University, New Haven, CT, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Biology, Yale University, New Haven, CT, U.S.A. | en_US |
dc.identifier.pmid | 2539881 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/28018/1/0000454.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0006-8993(89)90553-2 | en_US |
dc.identifier.source | Brain Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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