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Heterobifunctional cross-linking of a monoclonal antibody with 2-methyl-N1-benzenesulfonyl-N4-bromoacetylquinonediimide
dc.contributor.authorLiberatore, Frederick A.en_US
dc.contributor.authorComeau, Robert D.en_US
dc.contributor.authorLawton, Richard G.en_US
dc.date.accessioned2006-04-07T20:53:29Z
dc.date.available2006-04-07T20:53:29Z
dc.date.issued1989-02-15en_US
dc.identifier.citationLiberatore, Frederick A., Comeau, Robert D., Lawton, Richard G. (1989/02/15)."Heterobifunctional cross-linking of a monoclonal antibody with 2-methyl-N1-benzenesulfonyl-N4-bromoacetylquinonediimide." Biochemical and Biophysical Research Communications 158(3): 640-645. <http://hdl.handle.net/2027.42/28052>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WBK-4DYVHVW-3/2/83c8d2764a2e386cba9354601905794cen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/28052
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2920034&dopt=citationen_US
dc.description.abstractThe Cyssor reagent, 2-methyl-N1-benzenesulfonyl-N4-bromoacetylquinonediimide, which will cleave a protein chain at Cys under acidic conditions, cross-linked unreduced and partially reduced antibody at pH 8.0. No cleavage of the antibody occurred suggesting that the Cyssor reagent may be useful with certain proteins as a heterobifunctional cross-linker.en_US
dc.format.extent979634 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleHeterobifunctional cross-linking of a monoclonal antibody with 2-methyl-N1-benzenesulfonyl-N4-bromoacetylquinonediimideen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Chemistry, University of Michigan, 2525 Chemistry Building, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationotherImmunopharmaceutical Research and Development, Medical Products Department, E. I. du Pont de Nemours & Company, 331 Treble Cove Road, Bldg. 500-1, N., Billerica, MA 01862, USAen_US
dc.contributor.affiliationotherImmunopharmaceutical Research and Development, Medical Products Department, E. I. du Pont de Nemours & Company, 331 Treble Cove Road, Bldg. 500-1, N., Billerica, MA 01862, USAen_US
dc.identifier.pmid2920034en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/28052/1/0000491.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-291X(89)92769-1en_US
dc.identifier.sourceBiochemical and Biophysical Research Communicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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