Secretagogue induced calcium mobilization in single pancreatic acinar cells
dc.contributor.author | Stuenkel, Edward L. | en_US |
dc.contributor.author | Tsunoda, Yasuhiro | en_US |
dc.contributor.author | Williams, John A. | en_US |
dc.date.accessioned | 2006-04-07T20:53:31Z | |
dc.date.available | 2006-04-07T20:53:31Z | |
dc.date.issued | 1989-02-15 | en_US |
dc.identifier.citation | Stuenkel, Edward L., Tsunoda, Yasuhiro, Williams, John A. (1989/02/15)."Secretagogue induced calcium mobilization in single pancreatic acinar cells." Biochemical and Biophysical Research Communications 158(3): 863-869. <http://hdl.handle.net/2027.42/28053> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WBK-4DYVHVW-18/2/b29244ab377f28e61d544513448d6535 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/28053 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2920043&dopt=citation | en_US |
dc.description.abstract | Microspectrofluorometry of fura-2 was utilized to monitor [Ca2+]i in single acinar cells stimulated with a cholinergic agonist and cholecystokinin. A similar amplitude of agonist induced Ca mobilization between single cell and populational approaches was observed. New findings in single cells not observable in populations of cells include: 1) the maintenance of a sustained elevation in [Ca2+]i above basal levels throughout agonist application, 2) the reloading of the agonist-sensitive Ca pool only following removal of the agonist and 3) the presence of oscillations of [Ca2+]i in response to agonist application which is enhanced at lower agonist concentrations. | en_US |
dc.format.extent | 511580 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Secretagogue induced calcium mobilization in single pancreatic acinar cells | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Physiology, University of Michigan, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Physiology, University of Michigan, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Physiology, University of Michigan, Ann Arbor, MI 48109, USA | en_US |
dc.identifier.pmid | 2920043 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/28053/1/0000492.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0006-291X(89)92802-7 | en_US |
dc.identifier.source | Biochemical and Biophysical Research Communications | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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