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Secretagogue induced calcium mobilization in single pancreatic acinar cells

dc.contributor.authorStuenkel, Edward L.en_US
dc.contributor.authorTsunoda, Yasuhiroen_US
dc.contributor.authorWilliams, John A.en_US
dc.date.accessioned2006-04-07T20:53:31Z
dc.date.available2006-04-07T20:53:31Z
dc.date.issued1989-02-15en_US
dc.identifier.citationStuenkel, Edward L., Tsunoda, Yasuhiro, Williams, John A. (1989/02/15)."Secretagogue induced calcium mobilization in single pancreatic acinar cells." Biochemical and Biophysical Research Communications 158(3): 863-869. <http://hdl.handle.net/2027.42/28053>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WBK-4DYVHVW-18/2/b29244ab377f28e61d544513448d6535en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/28053
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2920043&dopt=citationen_US
dc.description.abstractMicrospectrofluorometry of fura-2 was utilized to monitor [Ca2+]i in single acinar cells stimulated with a cholinergic agonist and cholecystokinin. A similar amplitude of agonist induced Ca mobilization between single cell and populational approaches was observed. New findings in single cells not observable in populations of cells include: 1) the maintenance of a sustained elevation in [Ca2+]i above basal levels throughout agonist application, 2) the reloading of the agonist-sensitive Ca pool only following removal of the agonist and 3) the presence of oscillations of [Ca2+]i in response to agonist application which is enhanced at lower agonist concentrations.en_US
dc.format.extent511580 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleSecretagogue induced calcium mobilization in single pancreatic acinar cellsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Physiology, University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumDepartment of Physiology, University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumDepartment of Physiology, University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.identifier.pmid2920043en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/28053/1/0000492.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-291X(89)92802-7en_US
dc.identifier.sourceBiochemical and Biophysical Research Communicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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