Natriuresis associated with elevated plasma atrial natriuretic hormone during supraventricular tachycardia
dc.contributor.author | Nicklas, John M. | en_US |
dc.contributor.author | Giacherio, Donald A. | en_US |
dc.contributor.author | Moskowitz, David | en_US |
dc.contributor.author | Lemmer, John H. | en_US |
dc.contributor.author | Kirsh, Marvin M. | en_US |
dc.contributor.author | Grekin, Roger J. | en_US |
dc.date.accessioned | 2006-04-07T20:54:33Z | |
dc.date.available | 2006-04-07T20:54:33Z | |
dc.date.issued | 1989-02 | en_US |
dc.identifier.citation | Nicklas, John M., Giacherio, Donald A., Moskowitz, David, Lemmer, John H., Kirsh, Marvin M., Grekin, Roger J. (1989/02)."Natriuresis associated with elevated plasma atrial natriuretic hormone during supraventricular tachycardia." American Heart Journal 117(2): 377-381. <http://hdl.handle.net/2027.42/28078> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6W9H-4C548T2-10Y/2/3cb1dcd1d0b5f57a1f4a520220d95093 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/28078 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2521762&dopt=citation | en_US |
dc.description.abstract | Elevated plasma levels of atrial natriuretic hormone (ANH) have been found in patients during paroxysmal supraventricular tachycardia (SVT) and other clinical syndromes. However, physiologic effects of this endogenous ANH have not been demonstrated. To determine whether the rise in ANH during SVT is associated with either a natriuresis or kalluresis, urine sodium and potassium levels were measured in five patients at baseline and during SVT simulated by rapid atrioventricular pacing. Plasma ANH levels increased from 149 +/- 35 pmol/L at baseline to 387 +/- 31 pmol/L (p = 0.007) during SVT. Plasma vasopressin and renin levels were unchanged. Urine sodium levels increased 49% from 1.54 +/- 0.66 mEq/hr at baseline to 2.29 +/- 0.89 mEq/hr (p = 0.044) during SVT, and urine potassium levels increased 22% from 4.14 +/- 0.10 mEq/hr to 5.04 +/- 1.25 mEq/hr (p = 0.018). Urine sodium and potassium levels returned to baseline values 1 hour after pacing. Thus elevated plasma levels of ANH during SVT are associated with both a natriuresis and kalluresis, which may represent physiologic effects of the endogenously secreted hormone. | en_US |
dc.format.extent | 585616 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Natriuresis associated with elevated plasma atrial natriuretic hormone during supraventricular tachycardia | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Mich., USA | en_US |
dc.identifier.pmid | 2521762 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/28078/1/0000523.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-8703(89)90782-5 | en_US |
dc.identifier.source | American Heart Journal | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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