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Comparative actions of salicylate on the amphibian lateral line and guinea pig cochlea

dc.contributor.authorPuel, Jean Lucen_US
dc.contributor.authorBledsoe, Jr, Sanford C.en_US
dc.contributor.authorBobbin, Richard P.en_US
dc.contributor.authorMyers, Mark S.en_US
dc.contributor.authorCeasar, Gailen_US
dc.contributor.authorFallon, Maureenen_US
dc.date.accessioned2006-04-07T20:56:14Z
dc.date.available2006-04-07T20:56:14Z
dc.date.issued1989en_US
dc.identifier.citationPuel, Jean Luc, Bledsoe, Jr, Sanford C., Bobbin, Richard P., Myers, Mark S., Ceasar, Gail, Fallon, Maureen (1989)."Comparative actions of salicylate on the amphibian lateral line and guinea pig cochlea." Comparative Biochemistry and Physiology Part C: Comparative Pharmacology 93(1): 73-80. <http://hdl.handle.net/2027.42/28123>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B73F3-4CD9PKB-DH/2/34ac483df81f58d8a86a76109d8e80e5en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/28123
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2567228&dopt=citationen_US
dc.description.abstract1. 1. Salicylate actions on afferent nerve activity in the Xenopus lateral line and on cochlear potentials in guinea pig were investigated.2. 2. In the lateral line, salicylate (0.3-2.5 mM) suppressed spontaneous activity, water motion evoked excitation and responses to -glutamate (1-2 mM) and kainate (10-20[mu]M).3. 3. In the guinea pig, salicylate (0.6-10 mM) suppressed the compound action potential (CAP) and increased N1 latency at low but not high sound intensities.4. 4. In the lateral line salicylate action may involve an antagonism of the hair-cell transmitter on the afferent nerve.5. 5. In the cochlea salicylate may suppress the active process or cochlear amplifier.en_US
dc.format.extent901728 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleComparative actions of salicylate on the amphibian lateral line and guinea pig cochleaen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelKinesiology and Sportsen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumKresge Hearing Research Institute, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Telephone (504) 568-4785en_US
dc.contributor.affiliationotherLouisiana State University Medical School, Kresge Hearing Research Laboratory of the South, Department of Otorhinolaryngology, and Biocommunication, 2020 Gravier Street, Suite A, New Orleans, LA 70012, USAen_US
dc.contributor.affiliationotherLouisiana State University Medical School, Kresge Hearing Research Laboratory of the South, Department of Otorhinolaryngology, and Biocommunication, 2020 Gravier Street, Suite A, New Orleans, LA 70012, USAen_US
dc.contributor.affiliationotherLouisiana State University Medical School, Kresge Hearing Research Laboratory of the South, Department of Otorhinolaryngology, and Biocommunication, 2020 Gravier Street, Suite A, New Orleans, LA 70012, USAen_US
dc.contributor.affiliationotherLouisiana State University Medical School, Kresge Hearing Research Laboratory of the South, Department of Otorhinolaryngology, and Biocommunication, 2020 Gravier Street, Suite A, New Orleans, LA 70012, USAen_US
dc.contributor.affiliationotherLouisiana State University Medical School, Kresge Hearing Research Laboratory of the South, Department of Otorhinolaryngology, and Biocommunication, 2020 Gravier Street, Suite A, New Orleans, LA 70012, USAen_US
dc.identifier.pmid2567228en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/28123/1/0000573.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0742-8413(89)90013-3en_US
dc.identifier.sourceComparative Biochemistry and Physiology Part C: Comparative Pharmacologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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