Progress towards identifying the neurofibromatosis (NF1) gene
dc.contributor.author | Collins, Francis S. | en_US |
dc.contributor.author | O'Connell, Peter | en_US |
dc.contributor.author | Ponder, Bruce A. J. | en_US |
dc.contributor.author | Seizinger, Bernd R. | en_US |
dc.date.accessioned | 2006-04-07T20:57:24Z | |
dc.date.available | 2006-04-07T20:57:24Z | |
dc.date.issued | 1989 | en_US |
dc.identifier.citation | Collins, Francis S., O'Connell, Peter, Ponder, Bruce A. J., Seizinger, Bernd R. (1989)."Progress towards identifying the neurofibromatosis (NF1) gene." Trends in Genetics 5(): 217-221. <http://hdl.handle.net/2027.42/28154> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TCY-47PR8BH-31/2/0ed882c4732e047b117517220123a55e | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/28154 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2506682&dopt=citation | en_US |
dc.description.abstract | Von Recklinghausen neurofibromatosis (NF1) is a common autosomal dominant disorder of humans. Linkage analysis has recently mapped the NF1 gene to the proximal long arm of chromosome 17. The identification of two NF1 patients with balanced translocations has now allowed the location of the gene to be narrowed to a few hundred kilobases of chromosome band 17q11.2, using a combination of somatic cell hybrid technology, linking clones and pulsed field gel electrophoresis. | en_US |
dc.format.extent | 641572 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Progress towards identifying the neurofibromatosis (NF1) gene | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Genetics | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Howard Hughes Medical Institute, Departments of Human Genetics and Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationother | Howard Hughes Medical Institute, and Department of Human Genetics, University of Utah, Salt Lake City, UT 84132, USA | en_US |
dc.contributor.affiliationother | Cancer Research Campaign Human Cancer Genetics Research Group, University of Cambridge, UK | en_US |
dc.contributor.affiliationother | Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA | en_US |
dc.identifier.pmid | 2506682 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/28154/1/0000606.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0168-9525(89)90085-1 | en_US |
dc.identifier.source | Trends in Genetics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.