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Usefulness of a pericardial friction rub after thrombolytic therapy during acute myocardial infarction in predicting amount of myocardial damage

dc.contributor.authorWall, Thomas C.en_US
dc.contributor.authorCaliff, Robert M.en_US
dc.contributor.authorHarrelson-Woodlief, Lynnen_US
dc.contributor.authorMark, Daniel B.en_US
dc.contributor.authorHonan, Michaelen_US
dc.contributor.authorAbbottsmith, Charles W.en_US
dc.contributor.authorCandela, Richard J.en_US
dc.contributor.authorBerrios, Ericen_US
dc.contributor.authorPhillips, Harry R.en_US
dc.contributor.authorTopol, Eric J.en_US
dc.date.accessioned2006-04-10T13:32:05Z
dc.date.available2006-04-10T13:32:05Z
dc.date.issued1990-12-15en_US
dc.identifier.citationWall, Thomas C., Califf, Robert M., Harrelson-Woodlief, Lynn, Mark, Daniel B., Honan, Michael, Abbotsmith, Charles W., Candela, Richard, Berrios, Eric, Phillips, Harry R., Topol, Eric J. (1990/12/15)."Usefulness of a pericardial friction rub after thrombolytic therapy during acute myocardial infarction in predicting amount of myocardial damage." The American Journal of Cardiology 66(20): 1418-1421. <http://hdl.handle.net/2027.42/28271>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T10-4C76BNG-6H/2/ce7c2edddc50ae5ade82f5b7e60bf926en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/28271
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2123603&dopt=citationen_US
dc.description.abstractTo evaluate the clinical incidence and outcomes of patients with pericarditis after thrombolytic therapy, 810 patients were prospectively studied during acute myocardial infarction (AMI). Pericarditis was defined as the presence of a pericardial friction rub during the hospital course. Only 5% of patients developed a rub during AMI, a low percent compared with that in the prethrombolytic era. A pericardial friction rub more often occurred in the setting of an anterior wall AMI. Patients with, compared to those without, a pericardial friction rub had lower ejection fractions (45 vs 51%, P = 0.002); worse regional left ventricular function (-3.2 vs 2.7, standard deviation per chord); higher in-hospital mortality (15 vs 6%, P = 0.056); a higher frequency of power failure (83 vs 57%); a higher frequency of anterior wall location of the AMI (53% of cases, P = 0.002); and a higher frequency of 3-vessel disease. Therefore, although the frequency of a pericardial friction rub was low (5%) compared with that in the prethrombolytic era, its occurrence denotes more extensive myocardial damage with a worse clinical outcome. Perhaps with successful reperfusion of the infarct-related vessel, transmural myocardial necrosis is prevented and with it the development of pericarditis. Cardiac tamponade did not occur clinically in any patient who developed a pericardial friction rub.en_US
dc.format.extent517818 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleUsefulness of a pericardial friction rub after thrombolytic therapy during acute myocardial infarction in predicting amount of myocardial damageen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialtiesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA; University of Michigan Medical Center, Ann Arbor, Michigan, USA; Riverside Methodist Hospital, Columbus, Ohio, USA; Christ Hospital, Cincinnati, Ohio, USA.en_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan, USA; Riverside Methodist Hospital, Columbus, Ohio, USA; Christ Hospital, Cincinnati, Ohio, USA; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.en_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan, USA; Riverside Methodist Hospital, Columbus, Ohio, USA; Christ Hospital, Cincinnati, Ohio, USA; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.en_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan, USA; Riverside Methodist Hospital, Columbus, Ohio, USA; Christ Hospital, Cincinnati, Ohio, USA; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.en_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan, USA; Riverside Methodist Hospital, Columbus, Ohio, USA; Christ Hospital, Cincinnati, Ohio, USA; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.en_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan, USA; Riverside Methodist Hospital, Columbus, Ohio, USA; Christ Hospital, Cincinnati, Ohio, USA; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.en_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan, USA; Riverside Methodist Hospital, Columbus, Ohio, USA; Christ Hospital, Cincinnati, Ohio, USA; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.en_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan, USA; Riverside Methodist Hospital, Columbus, Ohio, USA; Christ Hospital, Cincinnati, Ohio, USA; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.en_US
dc.contributor.affiliationumUniversity of Michigan Medical Center, Ann Arbor, Michigan, USA; Riverside Methodist Hospital, Columbus, Ohio, USA; Christ Hospital, Cincinnati, Ohio, USA.en_US
dc.contributor.affiliationumDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA; University of Michigan Medical Center, Ann Arbor, Michigan, USA; Riverside Methodist Hospital, Columbus, Ohio, USA; Christ Hospital, Cincinnati, Ohio, USA.en_US
dc.identifier.pmid2123603en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/28271/1/0000020.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0002-9149(90)90526-7en_US
dc.identifier.sourceThe American Journal of Cardiologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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