Estrogen rapidly potentiates amphetamine-induced striatal dopamine release and rotational behavior during microdialysis
dc.contributor.author | Becker, Jill B. | en_US |
dc.date.accessioned | 2006-04-10T13:35:09Z | |
dc.date.available | 2006-04-10T13:35:09Z | |
dc.date.issued | 1990-10-16 | en_US |
dc.identifier.citation | Becker, Jill B. (1990/10/16)."Estrogen rapidly potentiates amphetamine-induced striatal dopamine release and rotational behavior during microdialysis." Neuroscience Letters 118(2): 169-171. <http://hdl.handle.net/2027.42/28348> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T0G-485RPVH-2CC/2/c1634b9a9a6f069d76dfda11dd193ef0 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/28348 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2125712&dopt=citation | en_US |
dc.description.abstract | Ovariectomy (OVX) of female rats results in a decreased behavioral response to stimulation of the mesostriatal dopamine (DA) system and decreased striatal DA release in vitro. Estrogen replacement restores both behavioral and neurochemical responsiveness. In this report, microdialysis in freely moving rats is used to simultaneously study the behavioral and neurochemical effects of systemic estradiol. OVX rats received a unilateral 6-hydroxy-dopamine lesion of the substantia nigra and then underwent microdialysis of the intact striatum. Thirty min after a single injection of 5 [mu]g estradiol benzoate, amphetamine-induced rotational behavior and striatal DA release are both potentiated, relative to the response of oil-treated control animals. | en_US |
dc.format.extent | 253146 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Estrogen rapidly potentiates amphetamine-induced striatal dopamine release and rotational behavior during microdialysis | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Psychology | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Social Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Psychology Department and Neuroscience Program, The University of Michigan, Ann Arbor, MI 48104-1687, U.S.A. | en_US |
dc.identifier.pmid | 2125712 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/28348/1/0000109.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0304-3940(90)90618-J | en_US |
dc.identifier.source | Neuroscience Letters | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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