Pulsed doppler evaluation of right ventricular diastolic filling in children with pulmonary valve stenosis before and after balloon valvuloplasty
dc.contributor.author | Vermilion, Roger P. | en_US |
dc.contributor.author | Snider, A. Rebecca | en_US |
dc.contributor.author | Meliones, Jon N. | en_US |
dc.contributor.author | Peters, Jane | en_US |
dc.contributor.author | Merida-Asmus, Lyne | en_US |
dc.date.accessioned | 2006-04-10T13:40:41Z | |
dc.date.available | 2006-04-10T13:40:41Z | |
dc.date.issued | 1990-07-01 | en_US |
dc.identifier.citation | Vermilion, Roger P., Snider, A. Rebecca, Meliones, Jon N., Peters, Jane, Merida-Asmus, Lyne (1990/07/01)."Pulsed doppler evaluation of right ventricular diastolic filling in children with pulmonary valve stenosis before and after balloon valvuloplasty." The American Journal of Cardiology 66(1): 79-84. <http://hdl.handle.net/2027.42/28486> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T10-4C6CRB3-2D/2/b2deea6b83bd9c4204114e06374fa643 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/28486 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2360536&dopt=citation | en_US |
dc.description.abstract | To assess right ventricular (RV) diastolic filling in children with pulmonary stenosis (PS), 14 patients (mean age 5.1 years) were examined immediately before and after pulmonary balloon valvuloplasty. Fourteen normal children (mean age 4.8 years) were also studied. From the tricuspid valve inflow Doppler study, the following measurements were made at peak inspiration: peak velocities at rapid filling (peak E) and during atrial contraction (peak A), ratio of peak E to peak A velocities, RV peak filling rate normalized for stroke volume, total area under the Doppler curve, percent of the total Doppler area occurring in the first third of diastole (0.33 area fraction), percent of the total area occurring under the E wave (E area fraction), percent of the total area occurring under the A wave (A area fraction) and the ratio of E area to A area. Before balloon valvuloplasty, the patients with PS had higher peak A velocity (0.64 +/- 0.28 vs 0.39 +/- 0.08 m/s), lower E/A velocity ratio (1.11 +/- 0.52 vs 1.76 +/- 0.45), lower 0.33 area fraction (0.34 +/- 0.14 vs 0.49 +/- 0.08), higher A area fraction (0.45 +/- 0.21 vs 0.27 +/- 0.09) and lower E/A area ratio (1.73 +/- 1.05 vs 2.96 +/- 1.14) than the normal subjects (p < 0.01). In patients before and after balloon valvuloplasty, there was a significant difference in RV outflow gradient (71 +/- 35 vs 28 +/- 15 mm Hg), but there was no change in any Doppler index. Thus, patients with PS have abnormal diastolic filling with decreased filling in early diastole and increased filling during atrial contraction. These abnormalities are unchanged immediately after successful relief of RV outflow obstruction, suggesting that hypertrophy rather than afterload mismatch is the primary determinant of the impaired relaxation. | en_US |
dc.format.extent | 1238063 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Pulsed doppler evaluation of right ventricular diastolic filling in children with pulmonary valve stenosis before and after balloon valvuloplasty | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.identifier.pmid | 2360536 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/28486/1/0000280.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-9149(90)90740-R | en_US |
dc.identifier.source | The American Journal of Cardiology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.