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PET and P300 relationships in early Alzheimer's disease
dc.contributor.authorMarsh, James T.en_US
dc.contributor.authorSchubarth, Glenaen_US
dc.contributor.authorBrown, Warren S.en_US
dc.contributor.authorRiege, Walteren_US
dc.contributor.authorStrandburg, Roberten_US
dc.contributor.authorDorsey, Deborahen_US
dc.contributor.authorMaltese, Adrianneen_US
dc.contributor.authorKuhl, David E.en_US
dc.date.accessioned2006-04-10T13:41:40Z
dc.date.available2006-04-10T13:41:40Z
dc.date.issued1990en_US
dc.identifier.citationMarsh, James T., Schubarth, Glena, Brown, Warren S., Riege, Walter, Strandburg, Robert, Dorsey, Deborah, Maltese, Adrianne, Kuhl, David (1990)."PET and P300 relationships in early Alzheimer's disease." Neurobiology of Aging 11(4): 471-476. <http://hdl.handle.net/2027.42/28511>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T09-487D3MH-1G/2/ad6fd5817295a40c4a591923b21a9399en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/28511
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2381507&dopt=citationen_US
dc.description.abstractThe P300 (P3) wave of the auditory brain event-related potential was investigated in patients with probable Alzheimer's disease to determine whether P300 latency discriminated these patients from controls and whether prolonged P300 latency correlated with rates of brain glucose metabolism as measured by Positron Emission Tomography. P300 latency was prolonged by more than 1.5 standard deviations from age expectancy in 14 of 18 patients, but none of 17 controls. In these subjects P300 latency was shown to be inversely correlated with relative metabolic rates of parietal and, to a lesser extent, temporal and frontal association areas, but not with subcortical areas.en_US
dc.format.extent633899 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titlePET and P300 relationships in early Alzheimer's diseaseen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Nuclear Medicine, University of Michigan Hospital, Ann Arbor, MI, U.S.A.en_US
dc.contributor.affiliationotherDepartment of Psychiatry and Biobehavioral Science and Brain Research Institute University of California, Los Angeles, CA, U.S.A.en_US
dc.contributor.affiliationotherEastern Nazarene College, Quincy, MA, U.S.A.en_US
dc.contributor.affiliationotherDepartment of Psychiatry and Biobehavioral Science and Brain Research Institute University of California, Los Angeles, CA, U.S.A.; Graduate School of Psychology, Fuller Theological Seminary, Pasadena, CA, U.S.A.en_US
dc.contributor.affiliationotherDepartment of Psychiatry and Biobehavioral Science and Brain Research Institute University of California, Los Angeles, CA, U.S.A.; V.A. Medical Center, Sepulveda, CA, U.S.A.en_US
dc.contributor.affiliationotherDepartment of Psychiatry and Biobehavioral Science and Brain Research Institute University of California, Los Angeles, CA, U.S.A.; Department of Psychology, Rhodes College, Memphis, TN, U.S.A.en_US
dc.contributor.affiliationotherCenter for the Health Sciences, University of California, Los Angeles, CA, U.S.A.en_US
dc.contributor.affiliationotherCenter for the Health Sciences, University of California, Los Angeles, CA, U.S.A.en_US
dc.identifier.pmid2381507en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/28511/1/0000308.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0197-4580(90)90015-Ren_US
dc.identifier.sourceNeurobiology of Agingen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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