Epileptiform abnormalities during sleep in Rett syndrome
dc.contributor.author | Aldrich, Michael S. | en_US |
dc.contributor.author | Garofalo, Elizabeth A. | en_US |
dc.contributor.author | Drury, Ivo | en_US |
dc.date.accessioned | 2006-04-10T13:45:24Z | |
dc.date.available | 2006-04-10T13:45:24Z | |
dc.date.issued | 1990-05 | en_US |
dc.identifier.citation | Aldrich, Michael S., Garofalo, Elizabeth A., Drury, Ivo (1990/05)."Epileptiform abnormalities during sleep in Rett syndrome." Electroencephalography and Clinical Neurophysiology 75(5): 365-370. <http://hdl.handle.net/2027.42/28605> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6SYX-485RKNY-39/2/f31b13e6cc9745cfe98ded48a2bb53cc | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/28605 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1692271&dopt=citation | en_US |
dc.description.abstract | We recorded all-night electroencephalograms (EEGs)/polysomnograms on 2 consecutive nights from 4 children (ages 4-11 years) with Rett syndrome. The first 10 sec of each 60 sec epoch were analyzed with counts of left and right hemisphere spikes and correlated with sleep stage. Spike counts were lowest during wakefulness. Spikes were most frequent over parasagittal regions during all sleep stages and varied from 0.28+/-0.03 to 40.4+/-0.7 (mean+/-S.E.M.) spikes/hemisphere/min. Spike counts were 51-109% higher during NREM sleep than during REM sleep. In 3 of 4 subjects, spikes were most frequent during light NREM sleep. Spikes increased in frequency during the second half of the night. We conclude that in Rett syndrome, epileptiform activity is maximally expressed in stage 1-2 NREM sleep and during the early morning hours. Sleep EEG features may be useful in the diagnosis of Rett syndrome. | en_US |
dc.format.extent | 412643 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Epileptiform abnormalities during sleep in Rett syndrome | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Neurology, University of Michigan, Ann Arbor, MI, U.S.A. | en_US |
dc.contributor.affiliationum | Division of Pediatric Neurology, University of Michigan, Ann Arbor, MI, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Neurology, University of Michigan, Ann Arbor, MI, U.S.A. | en_US |
dc.identifier.pmid | 1692271 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/28605/1/0000414.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0013-4694(90)90081-T | en_US |
dc.identifier.source | Electroencephalography and Clinical Neurophysiology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.