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Structure and chromosomal localization of the human thrombospondin gene
dc.contributor.authorWolf, Frederick W.en_US
dc.contributor.authorEddy, Roger L.en_US
dc.contributor.authorShows, Thomas B.en_US
dc.contributor.authorDixit, Vishva M.en_US
dc.date.accessioned2006-04-10T13:47:30Z
dc.date.available2006-04-10T13:47:30Z
dc.date.issued1990-04en_US
dc.identifier.citationWolf, Frederick W., Eddy, Roger L., Shows, Thomas B., Dixit, Vishva M. (1990/04)."Structure and chromosomal localization of the human thrombospondin gene." Genomics 6(4): 685-691. <http://hdl.handle.net/2027.42/28657>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WG1-4DNHPWK-BJ/2/3e22091a4f53fc4b290a302889dd705den_US
dc.identifier.urihttps://hdl.handle.net/2027.42/28657
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2341158&dopt=citationen_US
dc.description.abstractThrombospondin (THBS1) is a large modular glycoprotein component of the extracellular matrix and contains a variety of distinct domains, including three repeating subunits (types I, II, and III) that share homology to an assortment of other proteins. Determination of THBS1 gene structure has revealed that the type I repeat modules are encoded by symmetrical exons and that the heparin-binding domain is encoded by a single exon. To further elucidate the higher level organization of THBS1, the gene was localized to the q11-qter region of chromosome 15.en_US
dc.format.extent677853 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleStructure and chromosomal localization of the human thrombospondin geneen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pathology, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartment of Pathology, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationotherDepartment of Human Genetics, Roswell Park Memorial Institute, Buffalo, New York 14263, USAen_US
dc.contributor.affiliationotherDepartment of Human Genetics, Roswell Park Memorial Institute, Buffalo, New York 14263, USAen_US
dc.identifier.pmid2341158en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/28657/1/0000474.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0888-7543(90)90505-Oen_US
dc.identifier.sourceGenomicsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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