Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12
dc.contributor.author | Donlon, T. A. | en_US |
dc.contributor.author | Krensky, A. M. | en_US |
dc.contributor.author | Wallace, Margaret R. | en_US |
dc.contributor.author | Collins, Francis S. | en_US |
dc.contributor.author | Lovett, M. | en_US |
dc.contributor.author | Clayberger, C. | en_US |
dc.date.accessioned | 2006-04-10T13:49:52Z | |
dc.date.available | 2006-04-10T13:49:52Z | |
dc.date.issued | 1990-03 | en_US |
dc.identifier.citation | Donlon, T. A., Krensky, A. M., Wallace, M. R., Collins, F. S., Lovett, M., Clayberger, C. (1990/03)."Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12." Genomics 6(3): 548-553. <http://hdl.handle.net/2027.42/28717> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WG1-4DNHPNC-8J/2/2fb09fbffc98db8e501da3a7babc4af0 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/28717 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1691736&dopt=citation | en_US |
dc.description.abstract | We report here the localization of the gene for a human T-cell-specific molecule, designated RANTES, to human chromosome region 17q11.2-q12 by in situ hybridization and analysis of somatic cell hybrids using a cDNA probe to the gene. We have recently shown that this gene, which encodes a small, secreted, putative lymphokine, is a member of a larger gene family some of whose members reside on chromosome 4 but most of whose members have not to date been mapped. A secondary hybridization peak was noted on the region of human chromosome 5q31-q34, which may represent the location of other members of the gene family. Interestingly, this latter region overlaps with the location of an extended linked cluster of growth factor and receptor genes, some of which may be coregulated with members of the RANTES gene family. | en_US |
dc.format.extent | 2200834 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12 | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Genetics | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan 48109, USA. | en_US |
dc.contributor.affiliationother | Department of Pathology, Stanford University Medical Center, Stanford, California 94305, USA | en_US |
dc.contributor.affiliationother | Department of Pediatrics, Stanford University Medical Center, Stanford, California 94305, USA | en_US |
dc.contributor.affiliationother | Genelabs Incorporated, Redwood City, California 94063, USA | en_US |
dc.contributor.affiliationother | Department of Pediatrics, Stanford University Medical Center, Stanford, California 94305, USA | en_US |
dc.identifier.pmid | 1691736 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/28717/1/0000538.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0888-7543(90)90485-D | en_US |
dc.identifier.source | Genomics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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