Aging and the response to salmonella infection
dc.contributor.author | Bradley, Suzanne F. | en_US |
dc.contributor.author | Kauffman, Carol A. | en_US |
dc.date.accessioned | 2006-04-10T13:52:48Z | |
dc.date.available | 2006-04-10T13:52:48Z | |
dc.date.issued | 1990 | en_US |
dc.identifier.citation | Bradley, Suzzanne F., Kauffman, Carol A. (1990)."Aging and the response to salmonella infection." Experimental Gerontology 25(1): 75-80. <http://hdl.handle.net/2027.42/28791> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T6J-47RJ1GR-MC/2/ff3f84749fb35190d1f9403116e623b6 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/28791 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2180739&dopt=citation | en_US |
dc.description.abstract | We investigated the effect of age on the ability of Fischer 344 rats to mount a febrile response and contain infection due to Salmonella typhimurium. Elderly (22-23 month), middle-aged (12-13 month) and young (2-3 month) rats were inoculated intraperitoneally with 1.5 x 106 organisms and the febrile response and liver and spleen bacterial counts were followed for 13 days. The elderly had a more sluggish febrile response and did not achieve as great a maximum temperature elevation as the young and middle-aged rats. Except for days 1 and 5, bacterial counts in liver and spleen were greater in the elderly rats than in young and middle-aged rats. | en_US |
dc.format.extent | 409279 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Aging and the response to salmonella infection | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Geriatrics | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Veterans Administration Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Veterans Administration Medical Center, Ann Arbor, Michigan, USA | en_US |
dc.identifier.pmid | 2180739 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/28791/1/0000625.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0531-5565(90)90012-Q | en_US |
dc.identifier.source | Experimental Gerontology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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