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Aging and the response to salmonella infection

dc.contributor.authorBradley, Suzanne F.en_US
dc.contributor.authorKauffman, Carol A.en_US
dc.date.accessioned2006-04-10T13:52:48Z
dc.date.available2006-04-10T13:52:48Z
dc.date.issued1990en_US
dc.identifier.citationBradley, Suzzanne F., Kauffman, Carol A. (1990)."Aging and the response to salmonella infection." Experimental Gerontology 25(1): 75-80. <http://hdl.handle.net/2027.42/28791>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T6J-47RJ1GR-MC/2/ff3f84749fb35190d1f9403116e623b6en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/28791
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2180739&dopt=citationen_US
dc.description.abstractWe investigated the effect of age on the ability of Fischer 344 rats to mount a febrile response and contain infection due to Salmonella typhimurium. Elderly (22-23 month), middle-aged (12-13 month) and young (2-3 month) rats were inoculated intraperitoneally with 1.5 x 106 organisms and the febrile response and liver and spleen bacterial counts were followed for 13 days. The elderly had a more sluggish febrile response and did not achieve as great a maximum temperature elevation as the young and middle-aged rats. Except for days 1 and 5, bacterial counts in liver and spleen were greater in the elderly rats than in young and middle-aged rats.en_US
dc.format.extent409279 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleAging and the response to salmonella infectionen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelGeriatricsen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Veterans Administration Medical Center, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Veterans Administration Medical Center, Ann Arbor, Michigan, USAen_US
dc.identifier.pmid2180739en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/28791/1/0000625.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0531-5565(90)90012-Qen_US
dc.identifier.sourceExperimental Gerontologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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