Genetic and environmental effects on self-reported depressive symptoms in a general population twin sample
dc.contributor.author | Silberg, J. L. | en_US |
dc.contributor.author | Heath, Andrew C. | en_US |
dc.contributor.author | Kessler, R. | en_US |
dc.contributor.author | Neale, Michael C. | en_US |
dc.contributor.author | Meyer, J. M. | en_US |
dc.contributor.author | Eaves, Lindon J. | en_US |
dc.contributor.author | Kendler, Kenneth S. | en_US |
dc.date.accessioned | 2006-04-10T13:54:34Z | |
dc.date.available | 2006-04-10T13:54:34Z | |
dc.date.issued | 1990 | en_US |
dc.identifier.citation | Silberg, J. L., Heath, A. C., Kessler, R., Neale, M. C., Meyer, J. M., Eaves, L. J., Kendler, K. S. (1990)."Genetic and environmental effects on self-reported depressive symptoms in a general population twin sample." Journal of Psychiatric Research 24(3): 197-212. <http://hdl.handle.net/2027.42/28835> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T8T-4602RMS-K/2/116141679d32abf83a9daf8117cad85c | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/28835 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2266509&dopt=citation | en_US |
dc.description.abstract | To determine the etiology of self-reported depressive symptoms and their co-occurrence in the general population, multivariate genetic models were fitted to the responses of 771 female twin pairs (463 MZ, 308 DZ) to a 20-item epidemiological depression inventory (CES-D scale). A model which contained one common genetic factor, one shared environmental factor, and four unique environmental factors provided a useful account of symptom covariation. Under this model, the four non-shared environmental factors explained the largest proportion of variance in response to the CES-D scale, whereas a single common genetic factor explained substantially less of the variation in symptomatology. Consistent with previous findings (, , , & , Archives of General Psychiatry 43, 213-221, 1986) shared environmental influences were found to play a relatively minor role in the report of depressive symptoms. These results suggest that while genetic factors do contribute to the covariation among symptoms of depression, it is the largely non-shared environmental factors that account for the co-occurrence of symptoms in the general population. | en_US |
dc.format.extent | 1330010 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Genetic and environmental effects on self-reported depressive symptoms in a general population twin sample | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Institute For Social Research, University of Michigan, Box 1248, Ann Arbor, MI 48106-1248, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Human Genetics, Medical College of Virginia, Box 33, Richmond, VA 23298-0033, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Human Genetics, Medical College of Virginia, Box 33, Richmond, VA 23298-0033, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Psychiatry, Washington University Medical School, 4940 Audubon Avenue, St. Louis, MO 63110, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Psychology, Virginia Commonwealth University, Richmond, VA 23298, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Psychiatry, Medical College of Virginia, Box 710, Richmond, VA 23298, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Psychiatry, Medical College of Virginia, Box 710, Richmond, VA 23298, U.S.A. | en_US |
dc.identifier.pmid | 2266509 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/28835/1/0000670.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0022-3956(90)90010-N | en_US |
dc.identifier.source | Journal of Psychiatric Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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