Inorganic concepts relevant to metal binding, activity, and toxicity in a biological system
dc.contributor.author | Hoeschele, James D. | en_US |
dc.contributor.author | Turner, James E. | en_US |
dc.contributor.author | England, M. Wendy | en_US |
dc.date.accessioned | 2006-04-10T14:30:15Z | |
dc.date.available | 2006-04-10T14:30:15Z | |
dc.date.issued | 1991-12 | en_US |
dc.identifier.citation | Hoeschele, James D., Turner, James E., England, M. Wendy (1991/12)."Inorganic concepts relevant to metal binding, activity, and toxicity in a biological system." The Science of The Total Environment 109-110(): 477-492. <http://hdl.handle.net/2027.42/29015> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6V78-48XV1D6-RR/2/6f5557ca19d7abaab3cec5b6998a7b82 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/29015 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1815368&dopt=citation | en_US |
dc.description.abstract | Selected physical and inorganic concepts and factors which might be important in assessing and/or understanding the fate and disposition of metal compounds in a biological environment are reviewed. The stereochemistry (geometry), thermodynamic stability, redox properties, and intrinsic reactivity/lability are properties of metal compounds which can have a major influence on metal-target binding and on the eliciting of activity/toxicity. Concepts and factors are illustrated with appropriate examples where possible. Efforts to correlate the toxicity of metal compounds with a suitable indicator of toxicity should be expanded to include other parameters or combinations of parameters. | en_US |
dc.format.extent | 786358 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Inorganic concepts relevant to metal binding, activity, and toxicity in a biological system | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Women's and Gender Studies | en_US |
dc.subject.hlbsecondlevel | Social Work | en_US |
dc.subject.hlbsecondlevel | Obstetrics and Gynecology | en_US |
dc.subject.hlbsecondlevel | Geriatrics | en_US |
dc.subject.hlbsecondlevel | Gay/Lesbian/Bisexual/Transgender Studies | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Social Sciences | en_US |
dc.subject.hlbtoplevel | Humanities | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Chemistry, University of Michigan, 930 N. University Ave., Ann Arbor, MI 48109-1055, USA | en_US |
dc.contributor.affiliationother | Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831-6123, USA | en_US |
dc.contributor.affiliationother | Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831-6123, USA | en_US |
dc.identifier.pmid | 1815368 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/29015/1/0000044.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0048-9697(91)90202-P | en_US |
dc.identifier.source | The Science of The Total Environment | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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