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Ca2+-independent regulation of neurosecretion by intracellular Na+
dc.contributor.authorNordmann, Jean J.en_US
dc.contributor.authorStuenkel, Edward L.en_US
dc.date.accessioned2006-04-10T14:31:12Z
dc.date.available2006-04-10T14:31:12Z
dc.date.issued1991-11-04en_US
dc.identifier.citationNordmann, Jean J., Stuenkel, Edward L. (1991/11/04)."Ca2+-independent regulation of neurosecretion by intracellular Na+." FEBS Letters 292(1-2): 37-41. <http://hdl.handle.net/2027.42/29036>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T36-44XN3P8-XW/2/f34490695aec55a16b39263cf94bc7e0en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/29036
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1959623&dopt=citationen_US
dc.description.abstractWhile secretion from nerve endings is strictly controlled by an increase in cytoplasmic free calcium several reports suggest intracellular sodium may serve a regulatory role. Whether sodium acts directly to modulate secretion or indirectly by influencing cytoplasmic calcium dynamics is unknown. This study shows, based on parallel experiments studying [Na+]i, [Ca2+]i and vasopressin secretion, that sodium acts directly to regulate secretion in isolated nerve endings from the rat neurohypophysis. The elevation in secretion that develops is dose-dependently related to the [Na+]i and can occur in the absence of changes in [Ca2+]i.en_US
dc.format.extent596073 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleCa2+-independent regulation of neurosecretion by intracellular Na+en_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Physiology, 7744 Medical Sciences II Building, University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationotherCentre de Neurochimie CNRS, 5 rue Blaise Pascal, 67084 Strasbourg Cedex, Franceen_US
dc.identifier.pmid1959623en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/29036/1/0000069.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0014-5793(91)80828-Qen_US
dc.identifier.sourceFEBS Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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