Low oxygen delivery produced by anemia, hypoxia, and low cardiac output
dc.contributor.author | Cilley, Robert E. | en_US |
dc.contributor.author | Scharenberg, Andrew M. | en_US |
dc.contributor.author | Bongiorno, Phillip F. | en_US |
dc.contributor.author | Guire, Kenneth E. | en_US |
dc.contributor.author | Bartlett, Robert H. | en_US |
dc.date.accessioned | 2006-04-10T14:32:24Z | |
dc.date.available | 2006-04-10T14:32:24Z | |
dc.date.issued | 1991-11 | en_US |
dc.identifier.citation | Cilley, Robert E., Scharenberg, Andrew M., Bongiorno, Phillip F., Guire, Kenneth E., Bartlett, Robert H. (1991/11)."Low oxygen delivery produced by anemia, hypoxia, and low cardiac output." Journal of Surgical Research 51(5): 425-433. <http://hdl.handle.net/2027.42/29062> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WM6-4BNNVK8-D/2/691de8829f9bf4e2c4a6e639aa4a6d8c | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/29062 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1758176&dopt=citation | en_US |
dc.description.abstract | In pentobarbital-anesthetized dogs, oxygen delivery (DO2) was measured by thermodilution cardiac output and cooximeter determined oxygen content, while oxygen consumption (VO2) was measured independently by spirometry. Oxygen delivery was decreased by isovolemic dilutional anemia, breathing hypoxic gas mixtures, or cardiac tamponade to reduce cardiac output. Baseline VO2 (cc/kg/min) for the three groups was 5.9 +/- 0.7 (anemia), 5.4 +/- 0.4 (hypoxia), and 5.6 +/- 0.1 (low C.O.) (NS). A critical level of oxygen delivery (DO2crit) was found at 9-10 cc/kg/min (anemia), 10-11 cc/kg/min (hypoxia), and 9-10 cc/kg/min (low C.O.) (NS.). Below this level, VO2 fell (became supply dependent) and lactic acidosis occurred, regardless of the mechanism of impaired oxygen delivery. | en_US |
dc.format.extent | 947087 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Low oxygen delivery produced by anemia, hypoxia, and low cardiac output | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Surgery and Anesthesiology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Section of General Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109-0331, USA | en_US |
dc.contributor.affiliationum | Section of General Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109-0331, USA | en_US |
dc.contributor.affiliationum | Section of General Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109-0331, USA | en_US |
dc.contributor.affiliationum | Section of General Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109-0331, USA | en_US |
dc.contributor.affiliationum | Section of General Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109-0331, USA | en_US |
dc.identifier.pmid | 1758176 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/29062/1/0000095.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0022-4804(91)90145-C | en_US |
dc.identifier.source | Journal of Surgical Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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