Coronary bypass surgery improves global and regional left ventricular function following thrombolytic therapy for acute myocardial infarction
dc.contributor.author | Kereiakes, Dean J. | en_US |
dc.contributor.author | Califf, Robert M. | en_US |
dc.contributor.author | George, Barry S. | en_US |
dc.contributor.author | Ellis, Stephen G. | en_US |
dc.contributor.author | Samaha, Joseph | en_US |
dc.contributor.author | Stack, Richard S. | en_US |
dc.contributor.author | Martin, Linda H. | en_US |
dc.contributor.author | Young, Sharon Y. | en_US |
dc.contributor.author | Topol, Eric J. | en_US |
dc.date.accessioned | 2006-04-10T14:38:27Z | |
dc.date.available | 2006-04-10T14:38:27Z | |
dc.date.issued | 1991-08 | en_US |
dc.identifier.citation | Kereiakes, Dean J., Califf, Robert M., George, Barry S., Ellis, Stephen, Samaha, Joseph, Stack, Richard, Martin, Linda H., Young, Sharon, Topol, Eric J. (1991/08)."Coronary bypass surgery improves global and regional left ventricular function following thrombolytic therapy for acute myocardial infarction." American Heart Journal 122(2): 390-399. <http://hdl.handle.net/2027.42/29209> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6W9H-4BV49TK-20/2/545f3e0f3284fc9688fec59b61b16902 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/29209 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1907087&dopt=citation | en_US |
dc.description.abstract | Coronary bypass surgery was performed prior to hospital discharge in 303 (22%) of 1387 consecutive patients enrolled in the TAMI 1 to 3 and 5 trials of intravenous thrombolytic therapy for acute myocardial infarction. Bypass surgery was of emergency nature (24 hours) in 267 (19.3%) patients. The indications for bypass surgery included falled angioplasty (12%); left main or equivalent coronary disease (9%); complex or multivessel coronary disease (62%); recurrent postinfarction angina (13%); and refractory pump dysfunction, mitral regurgitation, ventricular septal rupture or abnormal predischarge functional test (1% each). Although patients having bypass surgery were older (59.5 +/- 9.8 versus 56.0 +/- 10.2 years, (p p p = 0.048), had more prior infarctions (p p = 0.0002), and regional infarct zone (-2.7 +/- 0.94 versus -2.5 +/- 1.1 SD/chord, p = 0.02) and noninfarct zone function (-0.36 +/- 1.8 versus 0.43 +/- 1.6 SD/chord, p p = 0.036) and infarct zone regional function (0.71 +/- 1.1 versus 0.34 +/- 0.99 SD/chord, p = 0.001) when immediate (90 minutes following initiation of thrombolytic therapy) and predischarge (7 to 14 days after treatment) contrast left ventriculograms were compared than did patients who received only intravenous thrombolytic therapy with or without coronary angioplasty. These data suggest a beneficial influence of coronary bypass surgery on left ventricular function and possibly on the clinical outcome of patients initially treated with intravenous thrombolytic therapy for acute myocardial infarction | en_US |
dc.format.extent | 1207780 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Coronary bypass surgery improves global and regional left ventricular function following thrombolytic therapy for acute myocardial infarction | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationother | The Christ Hospital Cardiovascular Research Center, Cincinnati, Ohio, USA | en_US |
dc.contributor.affiliationother | Division of Cardiology, Duke University, Durham, N.C., USA | en_US |
dc.contributor.affiliationother | Rivesside Methodist Hospital, Columbus, Ohio, USA | en_US |
dc.contributor.affiliationother | Division of Cardiology, Baptist Hospital, Memphis, Tenn., USA | en_US |
dc.contributor.affiliationother | Division of Cardiology, Duke University, Durham, N.C., USA | en_US |
dc.contributor.affiliationother | The Christ Hospital Cardiovascular Research Center, Cincinnati, Ohio, USA | en_US |
dc.contributor.affiliationother | Division of Cardiology, Duke University, Durham, N.C., USA | en_US |
dc.identifier.pmid | 1907087 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/29209/1/0000263.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-8703(91)90991-P | en_US |
dc.identifier.source | American Heart Journal | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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