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Thrombospondin production and thrombospondin-mediated adhesion in U937 cells
dc.contributor.authorVarani, Jamesen_US
dc.contributor.authorStoolman, Lloyd M.en_US
dc.contributor.authorWang, Tai-Lingen_US
dc.contributor.authorSchuger, Luciaen_US
dc.contributor.authorFlippen, C.en_US
dc.contributor.authorDame, Michael K.en_US
dc.contributor.authorJohnson, Kent J.en_US
dc.contributor.authorTodd, Robert F. IIIen_US
dc.contributor.authorRyan, Una S.en_US
dc.contributor.authorWard, Peter A.en_US
dc.date.accessioned2006-04-10T14:40:04Z
dc.date.available2006-04-10T14:40:04Z
dc.date.issued1991-07en_US
dc.identifier.citationVarani, J., Stoolman, L., Wang, T., Schuger, L., Flippen, C., Dame, M., Johnson, K. J., Todd, III, R. F., Ryan, U. S., Ward, P. A. (1991/07)."Thrombospondin production and thrombospondin-mediated adhesion in U937 cells." Experimental Cell Research 195(1): 177-182. <http://hdl.handle.net/2027.42/29248>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WFC-4DW346N-32/2/36a75cc43c2d8110eb196fde699f527cen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/29248
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2055266&dopt=citationen_US
dc.description.abstractU937 cells have low levels of surface thrombospondin (TSP) under control conditions but express higher levels after treatment for 1 day with 100 nM phorbol myristate acetate (PMA). Increased surface expression is due, in part, to increased biosynthesis. Untreated U937 cells do not adhere to TSP-coated plastic culture dishes but adhere strongly to TSP after stimulation with PMA. Untreated U937 cells also adhere weakly to endothelial cell monolayers while PMA-treated U937 cells attach strongly to monolayers of rat pulmonary artery endothelial cells. Endothelial cell adhesion appears to be mediated, in part, by TSP since antibodies to TSP partially inhibit.en_US
dc.format.extent2099154 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleThrombospondin production and thrombospondin-mediated adhesion in U937 cellsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumThe Departments of Pathology and Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Monsanto Corporation, 700 Chesterfield Parkway, Chesterfield, Missouri 63198, USAen_US
dc.contributor.affiliationumThe Departments of Pathology and Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Monsanto Corporation, 700 Chesterfield Parkway, Chesterfield, Missouri 63198, USAen_US
dc.contributor.affiliationumThe Departments of Pathology and Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Monsanto Corporation, 700 Chesterfield Parkway, Chesterfield, Missouri 63198, USAen_US
dc.contributor.affiliationumThe Departments of Pathology and Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Monsanto Corporation, 700 Chesterfield Parkway, Chesterfield, Missouri 63198, USAen_US
dc.contributor.affiliationumThe Departments of Pathology and Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Monsanto Corporation, 700 Chesterfield Parkway, Chesterfield, Missouri 63198, USAen_US
dc.contributor.affiliationumThe Departments of Pathology and Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Monsanto Corporation, 700 Chesterfield Parkway, Chesterfield, Missouri 63198, USAen_US
dc.contributor.affiliationumThe Departments of Pathology and Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Monsanto Corporation, 700 Chesterfield Parkway, Chesterfield, Missouri 63198, USAen_US
dc.contributor.affiliationumThe Departments of Pathology and Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Monsanto Corporation, 700 Chesterfield Parkway, Chesterfield, Missouri 63198, USAen_US
dc.contributor.affiliationumThe Departments of Pathology and Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Monsanto Corporation, 700 Chesterfield Parkway, Chesterfield, Missouri 63198, USAen_US
dc.contributor.affiliationumThe Departments of Pathology and Internal Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA; Monsanto Corporation, 700 Chesterfield Parkway, Chesterfield, Missouri 63198, USAen_US
dc.identifier.pmid2055266en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/29248/1/0000305.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0014-4827(91)90514-Uen_US
dc.identifier.sourceExperimental Cell Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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