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A calcium-activated, calcium-permeable ion channel in human retinal glial cells: modulation by basic fibroblast growth factor

dc.contributor.authorPuro, Donald G.en_US
dc.date.accessioned2006-04-10T14:43:27Z
dc.date.available2006-04-10T14:43:27Z
dc.date.issued1991-05-10en_US
dc.identifier.citationPuro, Donald G. (1991/05/10)."A calcium-activated, calcium-permeable ion channel in human retinal glial cells: modulation by basic fibroblast growth factor." Brain Research 548(1-2): 329-333. <http://hdl.handle.net/2027.42/29332>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6SYR-4834MFF-1PV/2/6edae60dbe93744ff198682bea0f6f2aen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/29332
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1651144&dopt=citationen_US
dc.description.abstractA calcium-permeable, voltage-insensitive non-specific cation channel that is activated by cytoplasmic calcium was found in approximately 50% of the cell-attached patches in cultured human retinal glial cells sampled by the patch clamp technique. Spontaneous openings of this channel were infrequent, but increased markedly when glial cells were exposed to basic fibroblast growth factor. Although the role of these cation channels is uncertain, they provide a mechanism to perpetuate a transient rise in cytosolic calcium induced by the release of calcium from intracellular stores.en_US
dc.format.extent445084 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleA calcium-activated, calcium-permeable ion channel in human retinal glial cells: modulation by basic fibroblast growth factoren_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartments of Ophthalmology and Physiology, University of Michigan School of Medicine, 1000 Wall Street, Ann Arbor, MI 48105, U.S.A.en_US
dc.identifier.pmid1651144en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/29332/1/0000399.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-8993(91)91143-Oen_US
dc.identifier.sourceBrain Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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