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Interleukin-1 induced gene expression of neutrophil activating protein (interleukin-8) and monocyte chemotactic peptide in human synovial cells
dc.contributor.authorDeMarco, Deborahen_US
dc.contributor.authorKunkel, Steven L.en_US
dc.contributor.authorStrieter, Robert M.en_US
dc.contributor.authorBasha, Michael A.en_US
dc.contributor.authorZurier, Robert B.en_US
dc.date.accessioned2006-04-10T14:49:52Z
dc.date.available2006-04-10T14:49:52Z
dc.date.issued1991-01-31en_US
dc.identifier.citationDeMarco, Deborah, Kunkel, Steyen L., Strieter, Robert M., Basha, Michael, Zurier, Robert B. (1991/01/31)."Interleukin-1 induced gene expression of neutrophil activating protein (interleukin-8) and monocyte chemotactic peptide in human synovial cells." Biochemical and Biophysical Research Communications 174(2): 411-416. <http://hdl.handle.net/2027.42/29493>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WBK-4F030CK-1/2/40daa0bfc4a11524ea57ed99983b4ab6en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/29493
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1993047&dopt=citationen_US
dc.description.abstractWe report here that human synovial cells stimulated by interleukin-1[alpha] and interleukin-1[beta] express mRNA for both IL-8 (neutrophil chemotactic peptide) and monocyte chemotactic protein. IL-1 stimulated synovial cells from both osteoarthritis and rheumatoid arthritis patients exhibited similar mRNA expression of interleukin-8 and monocyte chemotactic protein. A capacity to produce factors selectively chemotactic for neutrophils, lymphocytes and monocytes provides a mechanism whereby synovial cells can facilitate inflammatory arthritis.en_US
dc.format.extent549764 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleInterleukin-1 induced gene expression of neutrophil activating protein (interleukin-8) and monocyte chemotactic peptide in human synovial cellsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pathology, Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumDepartment of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumDepartment of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationotherRheumatology Section, Department of Medicine, Univerisity of Pennsylvania, Philadelphia, PA, USAen_US
dc.contributor.affiliationotherRheumatology Section, Department of Medicine, Univerisity of Pennsylvania, Philadelphia, PA, USAen_US
dc.identifier.pmid1993047en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/29493/1/0000579.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-291X(91)91431-Ben_US
dc.identifier.sourceBiochemical and Biophysical Research Communicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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