Changes in left ventricular diastolic filling during the development of left ventricular hypertrophy: Observations using Doppler echocardiography in a unique canine model
dc.contributor.author | Buda, Andrew J. | en_US |
dc.contributor.author | Li, Ying | en_US |
dc.contributor.author | Brant, David | en_US |
dc.contributor.author | Krause, Lisa C. | en_US |
dc.contributor.author | Julius, Stevo | en_US |
dc.date.accessioned | 2006-04-10T14:57:01Z | |
dc.date.available | 2006-04-10T14:57:01Z | |
dc.date.issued | 1991-06 | en_US |
dc.identifier.citation | Buda, Andrew J., Li, Ying, Brant, David, Krause, Lisa C., Julius, Stevo (1991/06)."Changes in left ventricular diastolic filling during the development of left ventricular hypertrophy: Observations using Doppler echocardiography in a unique canine model." American Heart Journal 121(6, Part 1): 1759-1767. <http://hdl.handle.net/2027.42/29670> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6W9H-4CN4KW3-13V/2/f2dd21db890c402582105ce05dba9fc1 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/29670 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1827937&dopt=citation | en_US |
dc.description.abstract | To examine changes in diastolic left ventricular filling during the development of left ventricular hypertrophy, serial pulsed Doppler echocardiographic studies were performed in a canine model of left ventricular hypertrophy induced by neurogenic pressor episodes. This model is unique since left ventricular hypertrophy develops without sustained hypertension. The neurogenic pressor episodes produced progressive increases in left ventricular mass of 17% by 3 weeks (p ) and of 23% by 9 weeks (p p p p r = -0.92, p < 0.001) but not at 9 weeks. These data indicate that left ventricular filling abnormalities occur early in the course of the development of left ventricular hypertrophy, are not a result of loading alterations related to sustained hypertension, and do not change significantly following increasing stages of hypertrophy. | en_US |
dc.format.extent | 946338 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Changes in left ventricular diastolic filling during the development of left ventricular hypertrophy: Observations using Doppler echocardiography in a unique canine model | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Divisions of Cardiology and Hypertension, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | Divisions of Cardiology and Hypertension, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | Divisions of Cardiology and Hypertension, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | Divisions of Cardiology and Hypertension, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | Divisions of Cardiology and Hypertension, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Mich., USA | en_US |
dc.identifier.pmid | 1827937 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/29670/1/0000759.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-8703(91)90023-B | en_US |
dc.identifier.source | American Heart Journal | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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