Effect of enalapril on myocardial infarction and unstable angina in patients with low ejection fractions
dc.contributor.author | Yusuf, Salim | en_US |
dc.contributor.author | Pepine, Carl J. | en_US |
dc.contributor.author | Garces, C. | en_US |
dc.contributor.author | Pouleur, H. | en_US |
dc.contributor.author | Rousseau, M. | en_US |
dc.contributor.author | Salem, Deeb | en_US |
dc.contributor.author | Kostis, John B. | en_US |
dc.contributor.author | Benedict, C. | en_US |
dc.contributor.author | Bourassa, Martial G. | en_US |
dc.contributor.author | Pitt, Bertram | en_US |
dc.date.accessioned | 2006-04-10T14:59:53Z | |
dc.date.available | 2006-04-10T14:59:53Z | |
dc.date.issued | 1992-11-14 | en_US |
dc.identifier.citation | Yusuf, S., Pepine, C. J., Garces, C., Pouleur, H., Rousseau, M., Salem, D., Kostis, J., Benedict, C., Bourassa, M., Pitt, B. (1992/11/14)."Effect of enalapril on myocardial infarction and unstable angina in patients with low ejection fractions." The Lancet 340(8829): 1173-1178. <http://hdl.handle.net/2027.42/29729> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T1B-49K56Y1-TY/2/28c59f4fcc59b024e3889039ce15cdc1 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/29729 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1359258&dopt=citation | en_US |
dc.description.abstract | An association between raised renin levels and myocardial infarction has been reported. We studied the effects of enalapril, an angiotensin-converting enzyme (ACE) inhibitor, on the development of myocardial infarction and unstable angina in 6797 patients with ejection fractions Patients were randomly assigned to placebo (n=3401) or enalapril (n=3396) at doses of 2[middle dot]5-20 mg per day in two concurrent double-blind trials with the same protocol. Patients with heart failure entered the treatment trial (n=2569) and those without heart failure entered the prevention trial (n=4228). Follow-up averaged 40 months. In each trial there were significant reductions in the number of patients developing myocardial infarction (treatment trial: 158 placebo vs 127 enalapril, PEnalapril treatment significantly reduced myocardial infarction, unstable angina, and cardiac mortality in patients with low ejection fractions. | en_US |
dc.format.extent | 770270 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Effect of enalapril on myocardial infarction and unstable angina in patients with low ejection fractions | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Medicine (General) | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | University of Michigan, Ann Arbor, United States | en_US |
dc.contributor.affiliationother | National Heart, Lung, and Blood Institute, Bethesda, Maryland, U.S.A. | en_US |
dc.contributor.affiliationother | University of Florida, Gainesville, United States | en_US |
dc.contributor.affiliationother | University of North Carolina, Chapel Hill, United States | en_US |
dc.contributor.affiliationother | University of Louvain, Belgium, United States | en_US |
dc.contributor.affiliationother | University of Louvain, Belgium, United States | en_US |
dc.contributor.affiliationother | New England Medical Center, Boston, United Kingdom | en_US |
dc.contributor.affiliationother | Robert Wood Johnson Medical Center, New Brunswick, New Jersey | en_US |
dc.contributor.affiliationother | University of Texas Medical Center, Houston, Canada | en_US |
dc.contributor.affiliationother | Montreal Heart Institute, Canada | en_US |
dc.identifier.pmid | 1359258 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/29729/1/0000065.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0140-6736(92)92889-N | en_US |
dc.identifier.source | The Lancet | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.