Isolation of a yeast artificial chromosome clone that spans the (12;16) translocation breakpoint characteristic of myxoid liposarcoma
dc.contributor.author | Gemmill, Robert M. | en_US |
dc.contributor.author | Mendez, Michael J. | en_US |
dc.contributor.author | Dougherty, Cynthia M. | en_US |
dc.contributor.author | Paulien, Sylvie | en_US |
dc.contributor.author | Liao, Martha | en_US |
dc.contributor.author | Mitchell, Deanna | en_US |
dc.contributor.author | Jankowski, Sheryl A. | en_US |
dc.contributor.author | Trent, Jeffrey M. | en_US |
dc.contributor.author | Berger, Carol S. | en_US |
dc.contributor.author | Sandberg, Avery A. | en_US |
dc.contributor.author | Meltzer, Paul S. | en_US |
dc.date.accessioned | 2006-04-10T15:05:41Z | |
dc.date.available | 2006-04-10T15:05:41Z | |
dc.date.issued | 1992-09 | en_US |
dc.identifier.citation | Gemmill, Robert M., Mendez, Michael J., Dougherty, Cynthia M., Paulien, Sylvie, Liao, Martha, Mitchell, Deanna, Jankowski, Sheryl A., Trent, Jeffrey M., Berger, Carol, Sandberg, Avery A., Meltzer, Paul S. (1992/09)."Isolation of a yeast artificial chromosome clone that spans the (12;16) translocation breakpoint characteristic of myxoid liposarcoma." Cancer Genetics and Cytogenetics 62(2): 166-170. <http://hdl.handle.net/2027.42/29862> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T53-47PYBK6-4X/2/70e17e419929449d4e873c01805761bc | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/29862 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1394104&dopt=citation | en_US |
dc.description.abstract | Cytogenetic analysis of liposarcomas has demonstrated that translocation (12;16) (q13.3;p11.2) is characteristic of the myxoid subtype of this adipose tissue tumor. Our previous results suggested that the GLI gene is close to the translocation breakpoint on chromosome 12. We now describe a yeast artificial chromosome (YAC) that contains GLI and spans the chromosome 12 region involved in the t(12;16) breakpoint. This clone will permit rapid definition of the genetic region surrounding the breakpoint and allow isolation of the gene presumably affected by the translocation. | en_US |
dc.format.extent | 433784 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Isolation of a yeast artificial chromosome clone that spans the (12;16) translocation breakpoint characteristic of myxoid liposarcoma | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Oncology and Hematology | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA; Eleanor Roosevelt Institute, Denver, Colorado, USA. | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA. | en_US |
dc.contributor.affiliationum | Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA. | en_US |
dc.contributor.affiliationother | Southwest Biomedical Research Institute, Scottsdale, Arizona, USA. | en_US |
dc.contributor.affiliationother | Southwest Biomedical Research Institute, Scottsdale, Arizona, USA. | en_US |
dc.identifier.pmid | 1394104 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/29862/1/0000210.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0165-4608(92)90257-9 | en_US |
dc.identifier.source | Cancer Genetics and Cytogenetics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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