Isolation and expression of the Drosophila drosulfakinin neural peptide gene product, DSK-I
dc.contributor.author | Nichols, Ruthann | en_US |
dc.date.accessioned | 2006-04-10T15:08:14Z | |
dc.date.available | 2006-04-10T15:08:14Z | |
dc.date.issued | 1992-08 | en_US |
dc.identifier.citation | Nichols, R. (1992/08)."Isolation and expression of the Drosophila drosulfakinin neural peptide gene product, DSK-I." Molecular and Cellular Neuroscience 3(4): 342-347. <http://hdl.handle.net/2027.42/29925> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WNB-4F0PTB1-9/2/c2c9776246c8dbe787183155d99f631d | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/29925 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=19912877&dopt=citation | en_US |
dc.description.abstract | The Drosophila drosulfakinin (dsk) gene encodes the cholecystokinin homologues drosulfakinin-I (DSK-I) and drosulfakinin-II (DSK-II). The naturally occurring DSKI peptide was isolated from an extract of adult flies and its sequence determined by automated Edman degradation and sequence-specific radioimmunoassay. The dsk cDNA is expressed during the larval, pupal, and adult stages of development and is an abundant adult head transcript. Sequence-specific DSK antibodies localized DSK expression in the Drosophila larval central nervous system to medial neurosecretory cells and projections that extend from the neurons anteriorly into the brain and posteriorly down the ventral ganglion. The availability of the dsk transcript, sequence-specific DSK antibodies and the application of molecular genetics provide the opportunity to elucidate the role(s) of Drosophila CCK homologues in brain structure and function. | en_US |
dc.format.extent | 1841112 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Isolation and expression of the Drosophila drosulfakinin neural peptide gene product, DSK-I | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Psychology | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Social Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Departments of Biological Chemistry and Biology, University of Michigan, Ann Arbor, Michigan 48109-1048, USA | en_US |
dc.identifier.pmid | 19912877 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/29925/1/0000282.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/1044-7431(92)90031-V | en_US |
dc.identifier.source | Molecular and Cellular Neuroscience | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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