EEG sleep in cushing's disease and cushing's syndrome: comparison with patients with major depressive disorder
dc.contributor.author | Shipley, James E. | en_US |
dc.contributor.author | Schteingart, David E. | en_US |
dc.contributor.author | Tandon, Rajiv | en_US |
dc.contributor.author | Pande, Atul C. | en_US |
dc.contributor.author | Grunhaus, Leon J. | en_US |
dc.contributor.author | Haskett, Roger F. | en_US |
dc.contributor.author | Starkman, Monica N. | en_US |
dc.date.accessioned | 2006-04-10T15:08:58Z | |
dc.date.available | 2006-04-10T15:08:58Z | |
dc.date.issued | 1992-07-15 | en_US |
dc.identifier.citation | Shipley, James E., Schteingart, David E., Tandon, Rajiv, Pande, Atul C., Grunhaus, Leon, Haskett, Roger F., Starkman, Monica N. (1992/07/15)."EEG sleep in cushing's disease and cushing's syndrome: comparison with patients with major depressive disorder." Biological Psychiatry 32(2): 146-155. <http://hdl.handle.net/2027.42/29943> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T4S-484F1Y8-28/2/883469077bd4caddd07170bbc3f52333 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/29943 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1330006&dopt=citation | en_US |
dc.description.abstract | Because patients with Cushing' syndrome (CS) and Major depressive disorder (MDD) share features of hypercortisolism and the depressive syndrome, we compared electroencephalographic (EEG) sleep in patients with pituitary-ACTH-dependent Cushing's syndrome (Cushing's disease, CD), patients with ACTH-independent Cushing's syndrome (AICS), patients with major depressive disorder (MDD), and normal subjects. There were substantial similarities in the abnormal polysomnography profiles of patients with CD, AICS, and MDD. All three patient groups demonstrated poorer sleep continuity, shortened rapid eye movement (REM) latency, and increased first REM period density compared with normal subjects. In addition, AICS patients and MDD patients had elevated REM activity and density. These findings are discussed in terms of models of pathophysiology that relate abnormalities in sleep, mood, and hypothalamic-pituitary-adrenal function. | en_US |
dc.format.extent | 839070 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | EEG sleep in cushing's disease and cushing's syndrome: comparison with patients with major depressive disorder | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Sleep Programs, Department of Psychiatry, Department of Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Division of Endocrinology and Metabolism, Department of Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Schizophrenia Programs, Department of Psychiatry, Department of Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Depression Programs, Department of Psychiatry, Department of Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Depression Programs, Department of Psychiatry, Department of Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Depression Programs, Department of Psychiatry, Department of Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Consultation-Liaison Programs, Department of Psychiatry, Department of Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA | en_US |
dc.identifier.pmid | 1330006 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/29943/1/0000301.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0006-3223(92)90017-T | en_US |
dc.identifier.source | Biological Psychiatry | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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