Excitatory amino acid binding sites in the trigeminal principal sensory and spinal trigeminal nuclei of the rat
dc.contributor.author | Tallaksen-Greene, Sara J. | en_US |
dc.contributor.author | Young, Anne B. | en_US |
dc.contributor.author | Penney, John B. | en_US |
dc.contributor.author | Beitz, Alvin J. | en_US |
dc.date.accessioned | 2006-04-10T15:09:10Z | |
dc.date.available | 2006-04-10T15:09:10Z | |
dc.date.issued | 1992-07-06 | en_US |
dc.identifier.citation | Tallaksen-Greene, Sara J., Young, Anne B., Penney, John B., Beitz, Alvin J. (1992/07/06)."Excitatory amino acid binding sites in the trigeminal principal sensory and spinal trigeminal nuclei of the rat." Neuroscience Letters 141(1): 79-83. <http://hdl.handle.net/2027.42/29948> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T0G-485TWJP-3VG/2/a52327ec02c4025985a0425609dc3d5b | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/29948 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1324445&dopt=citation | en_US |
dc.description.abstract | Quantitative autoradiography was used to examine the density and distribution of excitatory amino acid (EAA) binding site subtypes in the principal sensory and spinal trigeminal nuclei of the rat trigeminal complex. The highest densities of (NMDA), [alpha]-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid (AMPA), kainate and metabotropic receptors were found in the superficial laminae (I and II) of subnucleus caudalis, a region known to be densely innervated by primary afferent nociceptive terminals. Lower densities of EAA binding sites were observed in spinal subnuclei interpolaris and oralis and within the principal sensory nucleus. These results are consistent with the hypothesis that EAAs are involved in primary afferent nociceptive neurotransmission. | en_US |
dc.format.extent | 464796 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Excitatory amino acid binding sites in the trigeminal principal sensory and spinal trigeminal nuclei of the rat | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Psychology | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Social Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Veterinary Biology, University of Minnesota, St. Paul, MN, USA; Department of Neurology, University of Michigan, Ann Arbor, MI 48104-1687, USA. | en_US |
dc.contributor.affiliationum | Department of Neurology, University of Michigan, Ann Arbor, MI 48104-1687, USA | en_US |
dc.contributor.affiliationum | Department of Neurology, University of Michigan, Ann Arbor, MI 48104-1687, USA | en_US |
dc.contributor.affiliationother | Department of Veterinary Biology, University of Minnesota, St. Paul, MN, USA | en_US |
dc.identifier.pmid | 1324445 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/29948/1/0000306.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0304-3940(92)90339-9 | en_US |
dc.identifier.source | Neuroscience Letters | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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