Quantitative assessment of cartilage surface roughness in osteoarthritis using high frequency ultrasound
dc.contributor.author | Adler, Ronald S. | en_US |
dc.contributor.author | Dedrick, Dale K. | en_US |
dc.contributor.author | Laing, Timothy J. | en_US |
dc.contributor.author | Chiang, Edward H. | en_US |
dc.contributor.author | Meyer, Charles R. | en_US |
dc.contributor.author | Bland, Peyton H. | en_US |
dc.contributor.author | Rubin, Jonathan M. | en_US |
dc.date.accessioned | 2006-04-10T15:22:58Z | |
dc.date.available | 2006-04-10T15:22:58Z | |
dc.date.issued | 1992 | en_US |
dc.identifier.citation | Adler, Ronald S., Dedrick, Dale K., Laing, Timothy J., Chiang, Edward H., Meyer, Charles R., Bland, Peyton H., Rubin, Jonathan M. (1992)."Quantitative assessment of cartilage surface roughness in osteoarthritis using high frequency ultrasound." Ultrasound in Medicine & Biology 18(1): 51-58. <http://hdl.handle.net/2027.42/30279> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TD2-4C7V8R9-46/2/9b411efc47c5c72fb58cc7a04911e397 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/30279 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1566526&dopt=citation | en_US |
dc.description.abstract | Osteoarthritis (OA) is a common disease which affects nearly 50% of people over age 60. Histologic evaluation suggests that fibrillations ~20-150 [mu]m are among the earliest changes in the articular cartilage. We propose a technique to quantify these surface fibrillatory changes in osteoarthritic articular cartilage by considering the angular distribution of the envelope-detected backscattered pressure field from an incident 30-MHz focused transducer. The angular distribution of the scattered acoustic field from an insonifying source will directly relate to the distribution of surface fibrillatory changes. Data are presented for three different grades (400, 500 and 600 grit) of commercially available emory paper and three samples of osteoarthritic femoral head articular cartilage, which were visually assessed as having smooth, intermediate and rough surfaces, respectively. Our preliminary results indicate a probable monotonic relationship between articular cartilage roughening and the degree of broadening in the angle-dependent pressure amplitude. When applied to the emory paper, the technique indicates sensitivity to differences as small as ~5-10 [mu]m in mean roughness. This procedure may provide an extremely sensitive and reproducible means of quantifying and following the cartilage changes observed in early osteoarthritis. | en_US |
dc.format.extent | 668809 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Quantitative assessment of cartilage surface roughness in osteoarthritis using high frequency ultrasound | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Radiology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | University of Michigan Medical Center, Department of Radiology 1500 E. Medical Center Drive, Ann Arbor, MI 49109/0030, USA | en_US |
dc.contributor.affiliationum | University of Michigan Medical Center, Department of Radiology 1500 E. Medical Center Drive, Ann Arbor, MI 49109/0030, USA | en_US |
dc.contributor.affiliationum | University of Michigan Medical Center, Department of Radiology 1500 E. Medical Center Drive, Ann Arbor, MI 49109/0030, USA | en_US |
dc.contributor.affiliationum | University of Michigan Medical Center, Department of Radiology 1500 E. Medical Center Drive, Ann Arbor, MI 49109/0030, USA | en_US |
dc.contributor.affiliationum | University of Michigan Medical Center, Department of Radiology 1500 E. Medical Center Drive, Ann Arbor, MI 49109/0030, USA | en_US |
dc.contributor.affiliationother | Department of Orthopaedic Research Laboratories, Orthopaedic Surgery and Department of Internal Medicine, Rheumatology Division, 1500 E. Medical Center Drive, Ann Arbor, MI 49109/0030, USA | en_US |
dc.contributor.affiliationother | Department of Internal Medicine, Rheumatology Division, 1500 E. Medical Center Drive, Ann Arbor, MI 49109/0030, USA | en_US |
dc.identifier.pmid | 1566526 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/30279/1/0000680.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0301-5629(92)90008-X | en_US |
dc.identifier.source | Ultrasound in Medicine & Biology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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