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Synthesis of novel polyhydroxylated quinolizidines: Ring expanded analogs of glycosidase inhibitory indolizidines

dc.contributor.authorPearson, William H.en_US
dc.contributor.authorHembre, Erik J.en_US
dc.date.accessioned2006-04-10T15:28:12Z
dc.date.available2006-04-10T15:28:12Z
dc.date.issued1993-12-17en_US
dc.identifier.citationPearson, William H., Hembre, Erik J. (1993/12/17)."Synthesis of novel polyhydroxylated quinolizidines: Ring expanded analogs of glycosidase inhibitory indolizidines." Tetrahedron Letters 34(51): 8221-8224. <http://hdl.handle.net/2027.42/30391>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6THS-42H2JPH-T6/2/0739e925c1e712a91a81b1fe295b91c5en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/30391
dc.description.abstractTwo polyhydroxylated quinolizidines, (1R,2R,3R,9S,9aR)-1,2,3,9-tetrahydroxyquinolizidine 9 and (1R,2R,3R,9R,9aS-1,2,3,9-tetrahydroxyquinolizidine 10, have been synthesized by the reductive double cyclization of 15[alpha] and 15[beta]. Quinolizidine 9 can be viewed either as a ring expanded analog of 6-epicastanospermine or of 8-episwainsonine, while 10 is a ring expanded analog of 1,6,8a-triepicastanospermine or of 8a-episwainsonine.en_US
dc.format.extent272815 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleSynthesis of novel polyhydroxylated quinolizidines: Ring expanded analogs of glycosidase inhibitory indolizidinesen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMaterials Science and Engineeringen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1055 U.S.A.en_US
dc.contributor.affiliationumDepartment of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1055 U.S.A.en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/30391/1/0000009.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/S0040-4039(00)61395-3en_US
dc.identifier.sourceTetrahedron Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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