Chemical sequencing of disulfide-crosslinked oligodeoxyribonucleotides
dc.contributor.author | Swanson, Patrick C. | en_US |
dc.contributor.author | Glick, Gary D. | en_US |
dc.date.accessioned | 2006-04-10T15:35:30Z | |
dc.date.available | 2006-04-10T15:35:30Z | |
dc.date.issued | 1993-10 | en_US |
dc.identifier.citation | Swanson, Patrick C., Glick,, Gary D. (1993/10)."Chemical sequencing of disulfide-crosslinked oligodeoxyribonucleotides." Bioorganic & Medicinal Chemistry Letters 3(10): 2117-2118. <http://hdl.handle.net/2027.42/30570> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TF9-42P0F8Y-49/2/6758df10ad520b40a80f37a3f6482826 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/30570 | |
dc.description.abstract | Oligodeoxyribonucleotides containing a novel disulfide crosslink are shown to be amenable to chemical sequencing using standard sequencing reagents following reduction of the disulfide with DTT and selective alkylation of the free thiols with N-ethylmaleimide. This strategy will facilitate conformational and molecular recognition studies of DNA stabilized by crosslinking. | en_US |
dc.format.extent | 201067 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Chemical sequencing of disulfide-crosslinked oligodeoxyribonucleotides | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109-1055 U.S.A. | en_US |
dc.contributor.affiliationum | Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109-1055 U.S.A. | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/30570/1/0000205.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/S0960-894X(01)81028-3 | en_US |
dc.identifier.source | Bioorganic & Medicinal Chemistry Letters | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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