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Characterization of the genes encoding carbonic anhydrase I of chimpanzee and gorilla: comparative analysis of 5' flanking erythroid-specific promoter sequences
dc.contributor.authorEpperly, Bill R.en_US
dc.contributor.authorBergenhem, Nils C. H.en_US
dc.contributor.authorVenta, Patrick J.en_US
dc.contributor.authorTashian, Richard E.en_US
dc.date.accessioned2006-04-10T15:35:35Z
dc.date.available2006-04-10T15:35:35Z
dc.date.issued1993-09-15en_US
dc.identifier.citationEpperly, Bill R., Bergenhem, Nils C. H., Venta, Patrick J., Tashian, Richard E. (1993/09/15)."Characterization of the genes encoding carbonic anhydrase I of chimpanzee and gorilla: comparative analysis of 5' flanking erythroid-specific promoter sequences." Gene 131(2): 249-253. <http://hdl.handle.net/2027.42/30572>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T39-47PH9CK-2C6/2/f1614620e4f365728d8cc2aa3aa539e9en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/30572
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8406018&dopt=citationen_US
dc.description.abstractThe genes encoding carbonic anhydrase I (CA I) have been characterized for chimpanzee (Pan troglodytes) and gorilla (Gorilla gorilla). In addition, 44 nucleotides (nt) at the 5' end of the noncoding first exon (exon la), which is unique to the erythroid CA I mRNA, together with 188 nt of the adjacent 5' flanking regions, were sequenced for the corresponding positions of the CA I of orangutan, pigtail macaque, and squirrel monkey. When these 5' flanking regions are compared, along with those published for human and mouse CA I, they were found to contain several conserved sequences that may bind factors involved in the erythroid-specific expression of CA I. Comparisons of the human, chimpanzee, and gorilla coding and noncoding CA I sequences do not significantly deviate from a pattern of trichotomy for the evolutionary origins of these three hominoid species.en_US
dc.format.extent655799 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleCharacterization of the genes encoding carbonic anhydrase I of chimpanzee and gorilla: comparative analysis of 5' flanking erythroid-specific promoter sequencesen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109-0618, USAen_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109-0618, USAen_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109-0618, USAen_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109-0618, USAen_US
dc.identifier.pmid8406018en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/30572/1/0000207.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0378-1119(93)90301-Ien_US
dc.identifier.sourceGeneen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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