Phenelzine produces subsensitivity to nicotine
dc.contributor.author | Dilsaver, Steven C. | en_US |
dc.contributor.author | Hariharan, Meenatshisundanan | en_US |
dc.contributor.author | Davidson, Robin K. | en_US |
dc.date.accessioned | 2006-04-10T15:37:32Z | |
dc.date.available | 2006-04-10T15:37:32Z | |
dc.date.issued | 1993-09 | en_US |
dc.identifier.citation | Dilsaver, Steven C., Hariharan, Meenatshisundanan, Davidson, Robin K. (1993/09)."Phenelzine produces subsensitivity to nicotine." Progress in Neuro-Psychopharmacology and Biological Psychiatry 17(5): 847-860. <http://hdl.handle.net/2027.42/30616> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TBR-475CCTV-CY/2/c603d7facad5c3c2b4a2254e1288dec1 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/30616 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8255990&dopt=citation | en_US |
dc.description.abstract | Dilsaver, Steven C., Meenatshisundanan Hariharan, Robin K. Davidson: Phenelzine Produces Subsensitivity to Nicotine. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 1993, 17(5): 847-860. 1. 1. The authors attempted to detect a possible effect of treatment with phenelzine on a physiological response to nicotine in the rat.2. 2. Positive findings in an animal model suggest the feasibility of more complicated experiments in animals and the possibility of studies involving human subjects.3. 3. Treatment of Sprague Dawley rats (n = 10) with phenelzine sulfate (15.0 mg/kg ip) every 48 hours for 14 days was associated with a 73.3% decrease in the hypothermic response to nicotine.4. 4. Treatment with phenelzine did not enhance the rate of elimination of nicotine.5. 5. The authors discuss a possible relationship between changes in nicotinic mechanisms and the therapeutic actions of drugs used to treat affective illness. | en_US |
dc.format.extent | 892509 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Phenelzine produces subsensitivity to nicotine | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Psychiatry and Mental Health Research University of Michigan, U.S.A. | en_US |
dc.contributor.affiliationum | Department of Psychiatry and Mental Health Research University of Michigan, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Texas, Houston Clinical Research Unit Harris County Psychiatric Center Houston, Texas, U.S.A. | en_US |
dc.identifier.pmid | 8255990 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/30616/1/0000256.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0278-5846(93)90065-Z | en_US |
dc.identifier.source | Progress in Neuro-Psychopharmacology and Biological Psychiatry | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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