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Characterization of 10 New Polymorphic Dinucleotide Repeats and Generation of a High-Density Microsatellite-Based Physical Map of the BRCA1 Region of Chromosome 17q21
dc.contributor.authorCouch, Fergus J.en_US
dc.contributor.authorKiousis, Samen_US
dc.contributor.authorCastilla, Lucio H.en_US
dc.contributor.authorXu, Junzheen_US
dc.contributor.authorChandrasekharappa, Settara C.en_US
dc.contributor.authorChamberlain, Jeffrey S.en_US
dc.contributor.authorCollins, Francis S.en_US
dc.contributor.authorWeber, Barbara L.en_US
dc.date.accessioned2006-04-10T17:43:32Z
dc.date.available2006-04-10T17:43:32Z
dc.date.issued1994-12en_US
dc.identifier.citationCouch, Fergus J., Kiousis, Sam, Castilla, Lucio H., Xu, Junzhe, Chandrasekharappa, Settara C., Chamberlain, Jeffrey S., Collins, Francis S., Weber, Barbara L. (1994/12)."Characterization of 10 New Polymorphic Dinucleotide Repeats and Generation of a High-Density Microsatellite-Based Physical Map of the BRCA1 Region of Chromosome 17q21." Genomics 24(3): 419-424. <http://hdl.handle.net/2027.42/31157>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WG1-45PMRRP-9F/2/6495c44e2463516f1fdd598aec704b6aen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/31157
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7713491&dopt=citationen_US
dc.description.abstractA familial early onset breast cancer gene (BRCA1) has been localized to chromosome 17q21. To aid in the identification of this gene a number of new microsatellite markers from the D17S857 to D17S78 region were isolated and characterized. These markers, along with previously published markers from the region, were localized on a physical map by STS content mapping of cosmids from the BRCA1 interval. This high-density STS map of the BRCA1 region will be useful for linkage studies of families with apparent inherited breast cancer and for loss of heterozygosity analysis of breast tumor DNAs.en_US
dc.format.extent366284 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleCharacterization of 10 New Polymorphic Dinucleotide Repeats and Generation of a High-Density Microsatellite-Based Physical Map of the BRCA1 Region of Chromosome 17q21en_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan School of Medicine, and University of Michigan Human Genome Center, Ann Arbor, Michigan 48109, USA.en_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan School of Medicine, and University of Michigan Human Genome Center, Ann Arbor, Michigan 48109, USA.en_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan School of Medicine, Ann Arbor, Michigan 48109, USA; National Center for Human Genome Research, National Institutes of Health, Bethesda, Maryland 20892, USA.en_US
dc.contributor.affiliationotherDepartment of Internal Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.en_US
dc.contributor.affiliationotherNational Center for Human Genome Research, National Institutes of Health, Bethesda, Maryland 20892, USA.en_US
dc.contributor.affiliationotherDepartment of Internal Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104en_US
dc.contributor.affiliationotherNational Center for Human Genome Research, National Institutes of Health, Bethesda, Maryland 20892, USA.en_US
dc.contributor.affiliationotherDepartment of Internal Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104en_US
dc.identifier.pmid7713491en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/31157/1/0000056.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1006/geno.1994.1647en_US
dc.identifier.sourceGenomicsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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