Protein tyrosine phosphatases in disease processes
dc.contributor.author | Ninfa, Elizabeth G. | en_US |
dc.contributor.author | Dixon, Jack E. | en_US |
dc.date.accessioned | 2006-04-10T17:43:39Z | |
dc.date.available | 2006-04-10T17:43:39Z | |
dc.date.issued | 1994-12 | en_US |
dc.identifier.citation | Ninfa, Elizabeth G., Dixon, Jack E. (1994/12)."Protein tyrosine phosphatases in disease processes." Trends in Cell Biology 4(12): 427-430. <http://hdl.handle.net/2027.42/31159> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TCX-47GGPK5-3C/2/edd90436772710b3f61601612bf36bef | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/31159 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=14731691&dopt=citation | en_US |
dc.description.abstract | Given the importance of tyrosine phosphorylation of proteins in signalling pathways, it is perhaps not surprising that protein tyrosine phosphatases (PTPs) are involved in the pathogenesis of certain human diseases. A PTP produced by the Yersinia bacteria (which can cause bubonic plague, septicemia and enteric diseases) is thought to be used as a `weapon' against host cell functions. In addition, dysfunction of cells' endogenous PTPs may contribute to defective immune function, to cancer and to diabetes. | en_US |
dc.format.extent | 425446 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Protein tyrosine phosphatases in disease processes | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Biological Chemistry, The University of Michigan, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Biological Chemistry, The University of Michigan, Ann Arbor, MI 48109, USA | en_US |
dc.identifier.pmid | 14731691 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/31159/1/0000058.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0962-8924(94)90103-1 | en_US |
dc.identifier.source | Trends in Cell Biology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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