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Sources of Human Schwann Cells and the Influence of Donor Age
dc.contributor.authorBoyer, Philip J.en_US
dc.contributor.authorTuite, Gerald F.en_US
dc.contributor.authorDauser, Robert C.en_US
dc.contributor.authorMuraszko, Karin M.en_US
dc.contributor.authorTennekoon, Gihan I.en_US
dc.contributor.authorRutkowski, J. Lynnen_US
dc.date.accessioned2006-04-10T17:46:00Z
dc.date.available2006-04-10T17:46:00Z
dc.date.issued1994-11en_US
dc.identifier.citationBoyer, Philip J., Tuite, Gerald F., Dauser, Robert C., Muraszko, Karin M., Tennekoon, Gihan I., Rutkowski, J. Lynn (1994/11)."Sources of Human Schwann Cells and the Influence of Donor Age." Experimental Neurology 130(1): 53-55. <http://hdl.handle.net/2027.42/31199>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WFG-45NJTCM-7/2/b8eb4c66e448867c8105c88526b1495fen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/31199
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7821396&dopt=citationen_US
dc.description.abstractWe evaluated several tissues as possible sources for culturing human Schwann cells. The average cell yield (total cell number/mg of nerve fascicle) obtained from adult autopsy cases and transplant organ donors was similar (2 x 104 and 2.9 x 104, respectively), but significantly higher yields were obtained from dorsal roots of pediatric patients undergoing selective dorsal rhizotomy (6.1 x 104). Fresh tissue was not essential since cells isolated from 0 to 20 h postmortem were equally viable. However, we found evidence that donor age affects the intrinsic growth rate of Schwann cells and perineurial fibroblasts in culture.en_US
dc.format.extent134890 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleSources of Human Schwann Cells and the Influence of Donor Ageen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPsychiatryen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartments of Pediatrics, Neurology, Pathology, and Neurosurgery, The University of Michigan Medical Center, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartments of Pediatrics, Neurology, Pathology, and Neurosurgery, The University of Michigan Medical Center, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartments of Pediatrics, Neurology, Pathology, and Neurosurgery, The University of Michigan Medical Center, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartments of Pediatrics, Neurology, Pathology, and Neurosurgery, The University of Michigan Medical Center, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartments of Pediatrics, Neurology, Pathology, and Neurosurgery, The University of Michigan Medical Center, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartments of Pediatrics, Neurology, Pathology, and Neurosurgery, The University of Michigan Medical Center, Ann Arbor, Michigan 48109en_US
dc.identifier.pmid7821396en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/31199/1/0000101.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1006/exnr.1994.1184en_US
dc.identifier.sourceExperimental Neurologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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