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Synthesis of a disulfide cross-linked DNA triple helix
dc.contributor.authorGoodwin, Jay T.en_US
dc.contributor.authorOsborne, Scott E.en_US
dc.contributor.authorSwanson, Patrick C.en_US
dc.contributor.authorGlick, Gary D.en_US
dc.date.accessioned2006-04-10T18:03:50Z
dc.date.available2006-04-10T18:03:50Z
dc.date.issued1994-06-27en_US
dc.identifier.citationGoodwin, Jay T., Osborne, Scott E., Swanson, Patrick C., Glick,, Gary D. (1994/06/27)."Synthesis of a disulfide cross-linked DNA triple helix." Tetrahedron Letters 35(26): 4527-4530. <http://hdl.handle.net/2027.42/31493>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6THS-42HXCRS-XT/2/020603b73e2ded59b6b72bbdc67f0c8aen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/31493
dc.description.abstractAn intramolecular DNA triple helix incorporating a disulfide cross-link has been synthesized. Potassium permanganate footprinting and UV melting analysis demonstrate that the cross-link increases the conformational stability of this novel triplex at physiological pH and [Mg2+] relative to the unmodified sequence.en_US
dc.format.extent373106 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleSynthesis of a disulfide cross-linked DNA triple helixen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMaterials Science and Engineeringen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Chemistry University of Michigan Ann Arbor, Michigan 48109-1055 U.S.A.en_US
dc.contributor.affiliationumDepartment of Chemistry University of Michigan Ann Arbor, Michigan 48109-1055 U.S.A.en_US
dc.contributor.affiliationumDepartment of Chemistry University of Michigan Ann Arbor, Michigan 48109-1055 U.S.A.en_US
dc.contributor.affiliationumDepartment of Chemistry University of Michigan Ann Arbor, Michigan 48109-1055 U.S.A.en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/31493/1/0000415.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/S0040-4039(00)60718-9en_US
dc.identifier.sourceTetrahedron Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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