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Deletion analysis of the dystrophin-actin binding domain

dc.contributor.authorCorrado, Kathleenen_US
dc.contributor.authorMills, P. L.en_US
dc.contributor.authorChamberlain, Jeffrey S.en_US
dc.date.accessioned2006-04-10T18:08:52Z
dc.date.available2006-04-10T18:08:52Z
dc.date.issued1994-05-16en_US
dc.identifier.citationCorrado, K., Mills, P. L., Chamberlain, J. S. (1994/05/16)."Deletion analysis of the dystrophin-actin binding domain." FEBS Letters 344(2-3): 255-260. <http://hdl.handle.net/2027.42/31575>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T36-44M43WT-14N/2/c12e32030fbbf04d8b3bb97100efd90den_US
dc.identifier.urihttps://hdl.handle.net/2027.42/31575
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8187894&dopt=citationen_US
dc.description.abstractThree sequence motifs at the N-terminus of dystrophin have previously been proposed to be important for binding to actin. By analyzing a series of purified bacterial fusion proteins deleted for each of these sites we have demonstrated that none of the three are critical for dystrophin-actin interactions. Instead, our data suggest that sequences in the N-terminal 90 amino acids of dystrophin, excluding a conserved KTFT motif, contain the major site for interaction with actin.en_US
dc.format.extent747567 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleDeletion analysis of the dystrophin-actin binding domainen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan, Ann Arbor, MI 48109-0618, USAen_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan, Ann Arbor, MI 48109-0618, USAen_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan, Ann Arbor, MI 48109-0618, USAen_US
dc.identifier.pmid8187894en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/31575/1/0000503.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0014-5793(94)00397-1en_US
dc.identifier.sourceFEBS Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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