Atrial septal defect occlusion with the buttoned device (a multi-institutional U.S. trial)
dc.contributor.author | Lloyd, Thomas R. | en_US |
dc.contributor.author | Rao, P. Syamasundar | en_US |
dc.contributor.author | Beekman, III, Robert H. | en_US |
dc.contributor.author | Mendelsohn, Alan M. | en_US |
dc.contributor.author | Sideris, Eleftherios B. | en_US |
dc.date.accessioned | 2006-04-10T18:22:51Z | |
dc.date.available | 2006-04-10T18:22:51Z | |
dc.date.issued | 1994-02-01 | en_US |
dc.identifier.citation | Lloyd, Thomas R., Rao, P. Syamasundar, Beekman, III, Robert H., Mendelsohn, Alan M., Sideris, E. B. (1994/02/01)."Atrial septal defect occlusion with the buttoned device (a multi-institutional U.S. trial)." The American Journal of Cardiology 73(4): 286-291. <http://hdl.handle.net/2027.42/31816> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T10-4C7088N-MX/2/5bc5e147027f7617b42192854437cafd | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/31816 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8296761&dopt=citation | en_US |
dc.description.abstract | A clinical trial was conducted of the buttoned device for transcatheter closure of ostium secundum atrial septal defect. Occlusion was attempted in 57 patients aged 1 to 62 years (median 5). The procedure was abandoned in 7 patients after 1 or more unsuccessful attempts, and devices were released in 50 patients. Urgent surgical retrieval was necessary in 4 patients because of unstable device position: 3 devices "unbuttoned," with migration of the counteroccluder to the pulmonary artery or inferior vena cava, and 1 intact device embolized to the main pulmonary artery. All patients remained stable and underwent successful operation. Successful device implantation was therefore achieved in 46 patients, with immediate reduction in Qp/Qs from 1.8 +/- 0.6 to 1.1 +/- 0.2 (mean +/- SD, p < 0.0001). At most recent follow-up (1 to 20 months), 45 of 46 patients (98%) have no shunt or a trivial residual shunt. The prevalence of residual shunts declined from 65% at 1 month to 19% at 12 months after the occlusion procedure (p < 0.0001). Complications included unbuttoning of a fourth device, transient tricuspid regurgitation in 2 patients, and transient mitral regurgitation in 2 patients. An episode of asymptomatic atrial flutter was noted in a 46-year-old patient which may have been related to device implantation, but which has not recurred. There have been no cases of endocarditis or thromboembolism in 350 patient-months of follow-up. The buttoned device provided effective closure of the atrial septal defect in 45 of 57 patients (79%) in whom implantation was attempted and in 45 of 46 patients (98%) in whom device implantation was successfully accomplished. Unbuttoning remains the major complication of the procedure; increased operator experience and design modifications to the device may reduce the frequency of this problem in the future. | en_US |
dc.format.extent | 5594136 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Atrial septal defect occlusion with the buttoned device (a multi-institutional U.S. trial) | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Steele Memorial Children's Research Center, University Heart Center, and Department of Pediatrics (Cardiology), University of Arizona, Tucson, Arizona, USA; Division of Pediatric Cardiology, Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USA; Department of Pediatrics, Division of Pediatric Cardiology, University of Wisconsin Children's Hospital and University of Wisconsin Medical School, Madison, Wisconsin, USA; Pediatric Cardiology and Custom Medical Devices, Amarillo, Texas, USA. | en_US |
dc.contributor.affiliationum | Division of Pediatric Cardiology, Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USA; Department of Pediatrics, Division of Pediatric Cardiology, University of Wisconsin Children's Hospital and University of Wisconsin Medical School, Madison, Wisconsin, USA; Pediatric Cardiology and Custom Medical Devices, Amarillo, Texas, USA; Steele Memorial Children's Research Center, University Heart Center, and Department of Pediatrics (Cardiology), University of Arizona, Tucson, Arizona, USA. | en_US |
dc.contributor.affiliationum | Division of Pediatric Cardiology, Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USA; Department of Pediatrics, Division of Pediatric Cardiology, University of Wisconsin Children's Hospital and University of Wisconsin Medical School, Madison, Wisconsin, USA; Pediatric Cardiology and Custom Medical Devices, Amarillo, Texas, USA; Steele Memorial Children's Research Center, University Heart Center, and Department of Pediatrics (Cardiology), University of Arizona, Tucson, Arizona, USA. | en_US |
dc.contributor.affiliationum | Division of Pediatric Cardiology, Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USA; Department of Pediatrics, Division of Pediatric Cardiology, University of Wisconsin Children's Hospital and University of Wisconsin Medical School, Madison, Wisconsin, USA; Pediatric Cardiology and Custom Medical Devices, Amarillo, Texas, USA; Steele Memorial Children's Research Center, University Heart Center, and Department of Pediatrics (Cardiology), University of Arizona, Tucson, Arizona, USA. | en_US |
dc.contributor.affiliationum | Division of Pediatric Cardiology, Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USA; Department of Pediatrics, Division of Pediatric Cardiology, University of Wisconsin Children's Hospital and University of Wisconsin Medical School, Madison, Wisconsin, USA; Pediatric Cardiology and Custom Medical Devices, Amarillo, Texas, USA; Steele Memorial Children's Research Center, University Heart Center, and Department of Pediatrics (Cardiology), University of Arizona, Tucson, Arizona, USA. | en_US |
dc.identifier.pmid | 8296761 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/31816/1/0000762.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-9149(94)90235-6 | en_US |
dc.identifier.source | The American Journal of Cardiology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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