A mutant form of ornithine transcarbamylase found in a strain of Neurospora carrying a pyrimidine-proline suppressor gene
dc.contributor.author | Davis, Rowland H. | en_US |
dc.date.accessioned | 2006-04-13T14:55:20Z | |
dc.date.available | 2006-04-13T14:55:20Z | |
dc.date.issued | 1962-04 | en_US |
dc.identifier.citation | Davis, Rowland H. (1962/04)."A mutant form of ornithine transcarbamylase found in a strain of Neurospora carrying a pyrimidine-proline suppressor gene." Archives of Biochemistry and Biophysics 97(1): 185-191. <http://hdl.handle.net/2027.42/32313> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WB5-4DW2C90-6P/2/21ec07dd809edbb41329d683df1b1775 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/32313 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=13883962&dopt=citation | en_US |
dc.description.abstract | A mutation, s, of Neurospora, leads to a 98% reduction in ornithine transcarbamylase (OTC) activity without imposing an arginine requirement. It has been found that the enzyme present in the s strain is different from the normal enzyme in its affinities for ornithine and carbamyl phosphate. The affinity of the mutant enzyme for carbamyl phosphate is much greater than in the case of the wild type enzyme, and this characteristic could compensate to a large extent for the low specific activity in s strains. The data are used to indicate that the s locus is a gene which controls the structure of OTC in Neurospora. The possibility of there being two forms of this enzyme in wild type strains is discussed. | en_US |
dc.format.extent | 559017 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | A mutant form of ornithine transcarbamylase found in a strain of Neurospora carrying a pyrimidine-proline suppressor gene | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | From the Department of Botany, University of Michigan, cAnn Arbor, Michigan, USA | en_US |
dc.identifier.pmid | 13883962 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/32313/1/0000381.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0003-9861(62)90063-2 | en_US |
dc.identifier.source | Archives of Biochemistry and Biophysics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.