Metabolic effects of exercise in patients with type IV hyperlipoproteinemia
dc.contributor.author | Sannerstedt, Rune | en_US |
dc.contributor.author | Sanbar, Shafeek S. | en_US |
dc.contributor.author | Conway, James | en_US |
dc.date.accessioned | 2006-04-17T15:10:20Z | |
dc.date.available | 2006-04-17T15:10:20Z | |
dc.date.issued | 1970-06 | en_US |
dc.identifier.citation | Sannerstedt, Rune, Sanbar, Shafeek S., Conway, James (1970/06)."Metabolic effects of exercise in patients with type IV hyperlipoproteinemia." The American Journal of Cardiology 25(6): 642-648. <http://hdl.handle.net/2027.42/32754> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T10-4BP8RJW-20/2/4176cb68664864805f93b1888d58df18 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/32754 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=5420905&dopt=citation | en_US |
dc.description.abstract | Metabolic responses to 30 minutes of submaximal exercise were investigated in 11 healthy control subjects and 6 patients with type IV hyperlipoproteinemia (endogenous or essential hypertriglyceridemia). All subjects were male and ranged in age from 35 to 55 years. Before exercise they fasted overnight for at least 12 hours.The relative work performed, judged by the levels in heart rate and cardiac output on exercise, was comparable in the two groups, and the effects of exercise were qualitatively similar. Plasma glucose and triglyceride levels showed little change. Plasma concentration of cholesterol increased at the end of exercise by approximately 13 percent above control values compared to a concomitant increase in hematocrit of 3 percent. Plasma free fatty acid levels fell as exercise started and then returned to normal valves at the end of the 30 minutes of exercise; they then increased markedly after exercise but returned subsequently to control levels after 45 minutes.In response to muscular exercise, therefore, both control subjects and patients with type IV hyperlipoproteinemia significantly increase plasma cholesterol concentration. Subjects with hyperlipoproteinemia appear to mobilize free fatty acids in a normal manner for energy purposes, and the excess release of free fatty acids during exercise is apparently not derived from the abundantly circulating triglycerides; the latter were not altered by submaximal exercise. | en_US |
dc.format.extent | 798986 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Metabolic effects of exercise in patients with type IV hyperlipoproteinemia | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Clinical Physiology Unit, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Mich., U.S.A. | en_US |
dc.contributor.affiliationum | Clinical Physiology Unit, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Mich., U.S.A. | en_US |
dc.contributor.affiliationum | Clinical Physiology Unit, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Mich., U.S.A. | en_US |
dc.identifier.pmid | 5420905 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/32754/1/0000123.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-9149(70)90613-2 | en_US |
dc.identifier.source | The American Journal of Cardiology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.