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Studies on hypoxia--I. Gross and histologic influences of maternal anoxia upon the developing rat foetus

dc.contributor.authorMorawa, Arnolden_US
dc.contributor.authorHan, Seong Sooen_US
dc.date.accessioned2006-04-17T15:28:15Z
dc.date.available2006-04-17T15:28:15Z
dc.date.issued1968-07en_US
dc.identifier.citationMorawa, A. P., Han, S. S. (1968/07)."Studies on hypoxia--I. Gross and histologic influences of maternal anoxia upon the developing rat foetus." Archives of Oral Biology 13(7): 745-752. <http://hdl.handle.net/2027.42/33152>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T4J-4BWHGWV-H/2/395e19f1e42434fee95eed4f75707e9cen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/33152
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=5244298&dopt=citationen_US
dc.description.abstractAs the first communication of a series to be reported, this article represents the result of a survey work which was designed to serve as the basis for further experimentation on the subject. Effects of maternal anoxia upon the developing rat foetus were studied by subjecting pregnant Sprague-Dawley rats to an atmosphere of 100 per cent nitrogen for a total of 18 min on the 10th, 14th, 17th or 20th day of gestation and their offspring were then evaluated morphologically, radiographically, and histologically. All defects of skeletal morphology were found in newborns that were treated on the 10th day of gestation. The animals treated on the 20th day of gestation exhibited a consistent retardation in eruption of the molars. Histologically, a serious lag in the differentiation of epidermal and connective tissue cells was observed in animals subjected to anoxia on the 10th day, while an engorgement of the blood vessels was apparent in animals which were subjected to anoxia on the 20th day. These changes are discussed in relation to possible biochemical and physiologic effects of anoxia on these cells.en_US
dc.format.extent1127974 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleStudies on hypoxia--I. Gross and histologic influences of maternal anoxia upon the developing rat foetusen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelDentistryen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Oral Biology, School of Dentistry, and Department of Anatomy, Medical School, The University of Michigan, Ann Arbor, Michigan 48104, U.S.A.en_US
dc.contributor.affiliationumDepartment of Oral Biology, School of Dentistry, and Department of Anatomy, Medical School, The University of Michigan, Ann Arbor, Michigan 48104, U.S.A.en_US
dc.identifier.pmid5244298en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/33152/1/0000538.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0003-9969(68)90092-7en_US
dc.identifier.sourceArchives of Oral Biologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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