Mechanisms of onset and termination of abnormal cardiac rhythm studied by constant monitoring,
dc.contributor.author | Reynolds, Jr. , Ernest W. | en_US |
dc.contributor.author | MacDonald, Walter J. | en_US |
dc.contributor.author | Greenfield, Bruce M. | en_US |
dc.contributor.author | Semion, Alan A. | en_US |
dc.date.accessioned | 2006-04-17T15:34:01Z | |
dc.date.available | 2006-04-17T15:34:01Z | |
dc.date.issued | 1967-10 | en_US |
dc.identifier.citation | Reynolds, Jr., Ernest W., MacDonald, Walter J., Greenfield, Bruce M., Semion, Alan A. (1967/10)."Mechanisms of onset and termination of abnormal cardiac rhythm studied by constant monitoring,." American Heart Journal 74(4): 473-481. <http://hdl.handle.net/2027.42/33279> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6W9H-4C53FMN-131/2/91bdab131819eba7a41a41031e8a5ede | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/33279 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6053507&dopt=citation | en_US |
dc.description.abstract | Digitalis accelerated the rate in atrial flutter resulting in atrial fibrillation, whereas the addition of quinidine slowed the atrial rate producing either asystole or interference dissociation. In some patients receiving both digitalis and quinidine, the atrial rate showed less of a tendency to slow or actually increased, resulting in atrial fibrillation followed by normal sinus rhythm. This suggests an overriding effect of digitalis.Since the spontaneous termination of atrial flutter occurred in unknown circumstances that usually slowed the atrial rate and asystole was observed, this suggests that asystole is not a toxic effect of quinidine.Atrial flutter, fibrillation, and atrial premature beats began more commonly in the P-T cycle than in the T-P cycle. Since atrial recovery is more likely incomplete during the P-T cycle, this favors reentry as the underlying mechanism in the patient studied.Atrial and nodal tachycardia begin with an irregular sequence of premature beats before a stable tachycardia is established. There is usually a significant slowing of the rate prior to termination of the abnormal rhythm. Sinus arrest with ventricular escape is the usual method of termination, regardless of the form of therapy used. Bursts of rapid ventricular rhythm resembling ventricular tachycardia were seen only after the use of pressor agents.Atrial tachycardia with block treated with digitalis shows an initial atrial slowing but, as the dose of digitalis was raised in one patient, abrupt increases in atrial rate occurred until the rhythm terminated. This is a mechanism similar to that seen in the digitalis-induced termination of atrial flutter. | en_US |
dc.format.extent | 2625755 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Mechanisms of onset and termination of abnormal cardiac rhythm studied by constant monitoring, | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | University of Michigan Medical Center, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | University of Michigan Medical Center, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | University of Michigan Medical Center, Ann Arbor, Mich., USA | en_US |
dc.contributor.affiliationum | University of Michigan Medical Center, Ann Arbor, Mich., USA | en_US |
dc.identifier.pmid | 6053507 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/33279/1/0000671.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-8703(67)90005-1 | en_US |
dc.identifier.source | American Heart Journal | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.