Stimulation by octanoate of insulin release from isolated rat pancreas
dc.contributor.author | Sanbar, Shafeek S. | en_US |
dc.contributor.author | Martin, Julio M. | en_US |
dc.date.accessioned | 2006-04-17T16:11:29Z | |
dc.date.available | 2006-04-17T16:11:29Z | |
dc.date.issued | 1967-05 | en_US |
dc.identifier.citation | Sanbar, Shafeek S., Martin, Julio M. (1967/05)."Stimulation by octanoate of insulin release from isolated rat pancreas." Metabolism 16(5): 482-484. <http://hdl.handle.net/2027.42/33336> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WN4-4C4WC0C-6M/2/1686a2717859ff9c1d08647c6523acce | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/33336 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6025027&dopt=citation | en_US |
dc.description.abstract | Using pieces of rat pancreas incubated in Krebs-bicarbonate buffer containing 0.6 mg. glucose/ml., it has been found that addition of 3.0 mM. octanoate to the incubation medium significantly (p < .001) increased insulin release above control levels by 4.94 +/- 0.89 [mu]U. insulin/mg. of pancreatic tissue. Increasing the glucose concentration in the incubation medium to 3.0 mg./ml. without addition of octanoate produced a slightly smaller though significant (p < .05) increase in insulin release (2.96 +/- 0.96 [mu]U./mg.) above control levels. In conclusion, octanoate is capable of directly stimulating additional release of insulin by the beta-cells of the pancreas. | en_US |
dc.format.extent | 218897 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Stimulation by octanoate of insulin release from isolated rat pancreas | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Medicine (General) | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | The Research Institute, The Hospital for Sick Children, Toronto, Canada.; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | The Research Institute, The Hospital for Sick Children, Toronto, Canada.; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.identifier.pmid | 6025027 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/33336/1/0000733.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0026-0495(67)90140-0 | en_US |
dc.identifier.source | Metabolism | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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