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Stimulation by octanoate of insulin release from isolated rat pancreas
dc.contributor.authorSanbar, Shafeek S.en_US
dc.contributor.authorMartin, Julio M.en_US
dc.date.accessioned2006-04-17T16:11:29Z
dc.date.available2006-04-17T16:11:29Z
dc.date.issued1967-05en_US
dc.identifier.citationSanbar, Shafeek S., Martin, Julio M. (1967/05)."Stimulation by octanoate of insulin release from isolated rat pancreas." Metabolism 16(5): 482-484. <http://hdl.handle.net/2027.42/33336>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WN4-4C4WC0C-6M/2/1686a2717859ff9c1d08647c6523acceen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/33336
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6025027&dopt=citationen_US
dc.description.abstractUsing pieces of rat pancreas incubated in Krebs-bicarbonate buffer containing 0.6 mg. glucose/ml., it has been found that addition of 3.0 mM. octanoate to the incubation medium significantly (p &lt; .001) increased insulin release above control levels by 4.94 +/- 0.89 [mu]U. insulin/mg. of pancreatic tissue. Increasing the glucose concentration in the incubation medium to 3.0 mg./ml. without addition of octanoate produced a slightly smaller though significant (p &lt; .05) increase in insulin release (2.96 +/- 0.96 [mu]U./mg.) above control levels. In conclusion, octanoate is capable of directly stimulating additional release of insulin by the beta-cells of the pancreas.en_US
dc.format.extent218897 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleStimulation by octanoate of insulin release from isolated rat pancreasen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumThe Research Institute, The Hospital for Sick Children, Toronto, Canada.; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumThe Research Institute, The Hospital for Sick Children, Toronto, Canada.; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USAen_US
dc.identifier.pmid6025027en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/33336/1/0000733.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0026-0495(67)90140-0en_US
dc.identifier.sourceMetabolismen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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